NCT03956602

Brief Summary

The purpose of the present study was to determine the effects of different type of snack consumption on postprandial satiety, glucose, insulin, antioxidant capacity and anxiety in healthy subjects.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P75+ for not_applicable

Timeline
31mo left

Started Jan 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress76%
Jan 2018Dec 2028

Study Start

First participant enrolled

January 15, 2018

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

April 25, 2019

Completed
25 days until next milestone

First Posted

Study publicly available on registry

May 20, 2019

Completed
9.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Last Updated

January 21, 2026

Status Verified

January 1, 2026

Enrollment Period

10.9 years

First QC Date

April 25, 2019

Last Update Submit

January 16, 2026

Conditions

Satiety

Outcome Measures

Primary Outcomes (5)

  • Change of Satiety

    Hunger feeling (appetite) will be examined using visual analog scale (0-10): 0 least and 10 greatest

    0, 20, 40, 60, 90 and 120 minutes post snack consumption

  • Change of glucose level

    Blood will be collected by finger pricks and change of glucose level will be examined.

    0 and 40 minutes post snack consumption

  • Change of insulin level

    Blood will be collected by finger pricks and change of insulin level will be examined

    0 and 40 minutes post snack consumption

  • Change of anxiety feeling

    Anxiety feeling will examined using STAI (Spielberger Stasumte-Trait Anxiety Inventory) questionnaire (1-4): 1 least and 4 greatest, total summed score will be used.

    0 and 40 minutes post snack consumption

  • Change of antioxidant level

    Blood will be collected by finger pricks and change of antioxidant level will be examined

    0 and 40 minutes post snack consumption

Study Arms (7)

Pretzels

ACTIVE COMPARATOR

Subjects consume pretzels to examine postprandial response

Other: Pretzels

Brazil nuts

EXPERIMENTAL

Subjects consume Brazil nuts to examine postprandial response

Other: Brazil nuts

Potato chips

ACTIVE COMPARATOR

Subjects consume potato chips to examine postprandial response

Other: Potato chips

Mixed nuts

EXPERIMENTAL

Subjects consume mixed nuts to examine postprandial response

Other: Mixed nuts

White bread

ACTIVE COMPARATOR

Subjects consume white bread to examine postprandial response

Other: White bread

Dried mango

EXPERIMENTAL

Subjects consume dried mango to examine postprandial response

Other: Dried mango

Mango fruit

EXPERIMENTAL

Subjects consume fresh mango to examine postprandial response

Other: Mango fruit

Interventions

PretzelsOTHER

To examine postprandial responses of pretzel consumption

Pretzels
Brazil nutsOTHER

To examine postprandial responses of Brazil nut consumption

Brazil nuts
Potato chipsOTHER

To examine postprandial responses of potato chip consumption

Potato chips
Mixed nutsOTHER

To examine postprandial responses of mixed nut consumption

Mixed nuts
White breadOTHER

To examine postprandial responses of white bread consumption

White bread
Dried mangoOTHER

To examine postprandial responses of dried mango consumption

Dried mango
Mango fruitOTHER

To examine postprandial responses of fresh mango consumption

Mango fruit

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • years old

You may not qualify if:

  • Smoker
  • Pregnant woman
  • Required dietary supplement use
  • Required medication of metabolic disorders
  • Allergy to nuts or gluten (wheat)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Exercise and Nutritional Sciences, SDSU

San Diego, California, 92182-7251, United States

RECRUITING

Related Publications (1)

  • Stamper C, Safadi S, Gehr A, Asuncion P, Hong MY. Effects of fresh vs dried mango consumption on satiety and postprandial glucose in healthy adults. Metabol Open. 2023 Jul 18;19:100253. doi: 10.1016/j.metop.2023.100253. eCollection 2023 Sep.

    PMID: 37520177DERIVED

MeSH Terms

Interventions

Mangifera indica extract

Central Study Contacts

Mee Young Hong

CONTACT

6195942392mhong2@sdsu.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 25, 2019

First Posted

May 20, 2019

Study Start

January 15, 2018

Primary Completion (Estimated)

December 1, 2028

Study Completion (Estimated)

December 1, 2028

Last Updated

January 21, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations

US(1)