Association of Circulating Chemerin Levels and Arterial Stiffness
1 other identifier
observational
120
1 country
1
Brief Summary
Chemerin is a novel adipokine that might provide a link between chronic inflammation and obesity. Pulse wave velocity(PWV) is a useful method for examining arterial stiffness, meaning early-stage atherosclerosis. Therefore, in the present study, the investigators examined the relationship between circulating chemerin and arterial stiffness measured using PWV in obese persons.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2011
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2011
CompletedFirst Submitted
Initial submission to the registry
February 10, 2011
CompletedFirst Posted
Study publicly available on registry
February 11, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2011
CompletedMarch 4, 2011
January 1, 2011
28 days
February 10, 2011
March 3, 2011
Conditions
Outcome Measures
Primary Outcomes (1)
The difference of serum chemerin level between obese and non-obese groups
serum chemerin levels of all participants were by determined by an enzyme-linked immunosorbent assay (ELISA) kit (Biovender Laboratory Medicine Inc., Modrice, Czech Republic)
at the time of initial enrollment (4weeks)
Secondary Outcomes (1)
The correlation of serum chemerin levels with arterial stiffness
at the time of enrollment (4 weeks)
Study Arms (2)
Non- obese group
Obese group
Eligibility Criteria
Obese and age, gender matched non-obese group who underwent a medical health check in the Korea University Guro hospital
You may qualify if:
- Self referred persons for visiting routine medical check in our clinic
You may not qualify if:
- Malignancy
- Severe renal or hepatic disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Korea Universitylead
Study Sites (1)
Hye Jin Yoo
Seoul, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
February 10, 2011
First Posted
February 11, 2011
Study Start
February 1, 2011
Primary Completion
March 1, 2011
Study Completion
March 1, 2011
Last Updated
March 4, 2011
Record last verified: 2011-01