Key Insights

Highlights

Success Rate

94% trial completion (above average)

Published Results

876 trials with published results (12%)

Research Maturity

4982 completed trials (66% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

4.0%

299 terminated out of 7517 trials

Success Rate

94.3%

+7.8% vs benchmark

Late-Stage Pipeline

9%

670 trials in Phase 3/4

Results Transparency

18%

876 of 4982 completed with results

Key Signals

876 with results94% success299 terminated

Data Visualizations

Phase Distribution

5,995Total
Not Applicable (4313)
Early P 1 (75)
P 1 (446)
P 2 (491)
P 3 (340)
P 4 (330)

Trial Status

Completed4,982
Unknown844
Recruiting642
Active Not Recruiting304
Terminated299
Not Yet Recruiting189

Trial Success Rate

94.3%

Benchmark: 86.5%

Based on 4982 completed trials

Clinical Trials (7517)

Showing 20 of 20 trials
NCT05882045Phase 3CompletedPrimary

A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease

NCT07736729Not ApplicableNot Yet RecruitingPrimary

Continuous Wearable Biometric Monitoring in Adults Undergoing Obesity Treatment (SMART-BMI)

NCT05713799Phase 2Not Yet Recruiting

Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity

NCT07407348Phase 1Recruiting

A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body

NCT04684589Phase 2CompletedPrimary

Effect of PDE5 Inhibition on Adipose Metabolism in Humans

NCT05929079Phase 3Completed

A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight

NCT07564414Phase 3RecruitingPrimary

A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

NCT04335799Not ApplicableActive Not RecruitingPrimary

Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools

NCT07388537Not Yet RecruitingPrimary

Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults

NCT00342732CompletedPrimary

The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for Obesity

NCT07437976Not Yet RecruitingPrimary

A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity

NCT06972459Phase 3Active Not RecruitingPrimary

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related Comorbidity

NCT07734311Phase 3Not Yet Recruiting

A Study of Econoglutide Injection in Obese Participants With Knee Osteoarthritis (KOA)

NCT07732738Not ApplicableRecruitingPrimary

Bariatric Surgery Combined With GLP-1RA: A Multicenter Study.

NCT07702890Phase 1RecruitingPrimary

A Three-part First-in-human Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GUB-UCN2 in Healthy Lean and Obese Participants and Participants With T2D

NCT07437079Phase 1Recruiting

A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or Obesity

NCT07225556Phase 1Active Not Recruiting

A Study of LY4167586 in Participants With Obesity or Overweight Who Are Otherwise Healthy

NCT04463407Not ApplicableCompletedPrimary

Effect of a Single Nutritional Intervention Previous to a Critical Period of Fat Gain in University Students With Overweight and Obesity

NCT01399385Not ApplicableRecruiting

New Heart Imaging Techniques to Evaluate Possible Heart Disease

NCT07731412Not ApplicableCompletedPrimary

Short-Term Changes in Salivary IL-6, TNF-α, and Periodontal Inflammation Following Sleeve Gastrectomy in Patients With Obesity: A Randomized Controlled Pilot Study

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