Effect of Pyramidal Training on Selected Risk Factors of Atherosclerosis

NCT06077552 | Completed

• 1 other identifier: P.T.REC/012/004666
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The study will be conducted on fifty women with central obesity. Their ages will be from 30-40 years old. They will be selected from Al Hayat specialized Hospital in Cairo, Egypt and The participants will be randomly assigned into two equal groups: Group (A): study group, 25 participants will receive pyramidal training by treadmill for 40 minutes per session three sessions per week for eight weeks in addition to the diet health advices. Group (B): Control group, 25 participants will receive diet health advices. The subjects will be selected from El Haya specialized Hospital, Cairo.

Conditions

Obesity; Atherosclerosis

Keywords

obesity; risk factor; lipid profile

Outcome Measures

Primary Outcomes (1)

• atherogenic index of plasma

  blood analysis

  8 weeks

Secondary Outcomes (4)

• Waist circumference

  8 weeks

• Body mass index

  8 weeks

• lipid profile

  8 weeks

• insulin resistance

  8 weeks

Study Arms (2)

experimental group

EXPERIMENTAL

pyramidal training by treadmill for 40 minutes per session three sessions per week for eight weeks in addition to the diet health advises.

Other: pyramidal training by treadmill

control group

NO INTERVENTION

receive diet health advises.

Interventions

pyramidal training by treadmill OTHER

pyramidal training by treadmill for 40 minutes per session three sessions per week for eight weeks in addition to the diet health advises

experimental group

Eligibility Criteria

• Age: 30 Years - 40 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• \) Fifty women with central obesity. 2) Waist circumference \> 88 cm. 3) Their age will be ranged from 30-40years old. 4) Body mass index (BMI) from 30 to 34.9 kg/m2. 5) High normal or abnormal lipid profile (total cholesterol \> 200 mg/dl, HDL\< 35 mg/dl, or triglycerides \>150 mg/dl) and atherogenic index of plasma (AIP) ranges 0.11-0.21 6) HOMA-IR \> 2.9 7) They are clinically and medically stable. 8) All participants are sedentary activity level according to physical activity index.

You may not qualify if:

• \) Participants with musculoskeletal problems (e.g., Sever osteoarthritis or difficulties in ambulation).
• \) Participants with uncontrolled pulmonary disease. (e.g., Exaggerated chronic obstructive pulmonary disease, acute asthma).
• \) Any participants who missed more than two weeks of the program or want to terminate the program.
• \) Participants with unstable angina, uncontrolled cardiac arrhythmia, decompensated heart failure.
• \) The participants have hearing impairment or mental disorders. 6) Implanted pacemaker. 7) Diabetes and hypertension.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy

Cairo, Dokki, 11432, Egypt

Location

MeSH Terms

Conditions

Obesity; Atherosclerosis

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Marwa elsayed, PhD

  Cairo University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: October 5, 2023
• First Posted: October 11, 2023
• Study Start: November 1, 2023
• Primary Completion: December 30, 2024
• Study Completion: January 30, 2025
• Last Updated: February 18, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: after 4 years of publishing
• Access Criteria: publishing journal web site

Locations

EG (1)