NCT01215630

Brief Summary

The primary aim is to study the relationship between vascular function, cardiovascular fitness and age in healthy subjects. Individuals with the highest cardiovascular fitness will have the greatest arterial inflow independent of age.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Oct 2010

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2010

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

October 4, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 6, 2010

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2012

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2012

Completed
Last Updated

February 9, 2017

Status Verified

February 1, 2017

Enrollment Period

1.4 years

First QC Date

October 4, 2010

Last Update Submit

February 7, 2017

Conditions

Healthy Subjects

Keywords

VeinsExercise testsmaximal oxygen uptakeVO2max

Outcome Measures

Primary Outcomes (1)

  • Venous Compliance

    Echocardiography; Test - retest

    2 weeks

Secondary Outcomes (1)

  • Maximal oxygen uptake

    one test at baseline

Study Arms (1)

Healthy subjects

Men Women Age; 18-75

Behavioral: Aerobic Interval Training

Interventions

Aerobic Interval TrainingBEHAVIORAL

One interval training session

Healthy subjects

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Healthy men and women, aged 18-75 yrs

You may qualify if:

  • Healthy subjects, 18-75 years of age

You may not qualify if:

  • Inability to exercise due to musculoskeletal conditions
  • Known ischemic cardiovascular disease
  • Smoking or tobacco use
  • Acute medical conditions
  • Active infections
  • Pharmacotherapy with known vascular effects

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Norwegian University of Science and Technology

Trondheim, 7491, Norway

Location

Related Publications (2)

  • Leinan IM, Aamot IL, Stoylen A, Karlsen T, Wisloff U. Upper arm venous compliance and fitness in stable coronary artery disease patients and healthy controls. Clin Physiol Funct Imaging. 2017 Sep;37(5):498-506. doi: 10.1111/cpf.12324. Epub 2015 Dec 15.

    PMID: 26667796RESULT

  • Leinan IM, Grønnevik Ø, Støylen A, Wisløff U, Karlsen T. A cross sectional study of arm venous compliance in fit healthy subjects. Journal of Cardiovascular Research 1(2). http://www.vipoa.org/journals/pdf/5947267721.pdf

    RESULT

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood samples

Study Officials

  • Trine Karlsen, PhD

    Norwegian University of Science and Technology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 4, 2010

First Posted

October 6, 2010

Study Start

October 1, 2010

Primary Completion

March 1, 2012

Study Completion

May 1, 2012

Last Updated

February 9, 2017

Record last verified: 2017-02

Locations

NO(1)