Effect of Exercise on Heart Function in Healthy Elderly People
Aerobic Interval Training Reduces and Compensates Age Related Decline in Cardiac Function
1 other identifier
interventional
45
1 country
1
Brief Summary
The purpose of this study is to determine the effect of aerobic interval training on left- and right ventricular diastolic- and systolic function on healthy, sedate people over 70 years. The old sedate cohort will be compared to young, sedate subjects also performing aerobic interval training and old master athletes without intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Nov 2008
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2008
CompletedFirst Submitted
Initial submission to the registry
December 8, 2008
CompletedFirst Posted
Study publicly available on registry
December 9, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2009
CompletedJuly 18, 2016
July 1, 2016
4 months
December 8, 2008
July 15, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Improvement of left and right ventricular early diastolic tissue velocity at rest and sub maximal exercise ,e'.
12 weeks
Secondary Outcomes (1)
Improvement of left and right ventricular systolic tissue velocity function at rest and sub maximal exercise, S'.
12weeks
Study Arms (1)
Exercise intervention
EXPERIMENTALInterventions
High intensity aerobic interval training consists of 10 minutes warm up at \~60% of maximal heart rate, 4x4 minutes intervals at 90-95 % of maximal heart rate corresponding to 85-90% of VO2max) walking/running uphill on a treadmill, with three minutes active pause between the exercise bouts at 60-70% maximal heart rate. The session is terminated with 3 minutes cool down. Total exercise time is 38 minutes.The training is supervised by an exercise physiologist and the subjects train 3 times per week for 12 weeks.
Eligibility Criteria
You may qualify if:
- over 70 years, healthy
- not exercising more than twice per week
You may not qualify if:
- chronic illness
- chronic use of any medication
- regular smoking
- metabolic or cardiovascular diseases
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ntnu/Dmf/Isb
Trondheim, Sør-Trøndelag, 7489, Norway
Related Publications (1)
Molmen HE, Wisloff U, Aamot IL, Stoylen A, Ingul CB. Aerobic interval training compensates age related decline in cardiac function. Scand Cardiovasc J. 2012 Jun;46(3):163-71. doi: 10.3109/14017431.2012.660192. Epub 2012 Feb 20.
PMID: 22273242RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Charlotte Bjork Ingul, PhD
National Taiwan Normal University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 8, 2008
First Posted
December 9, 2008
Study Start
November 1, 2008
Primary Completion
March 1, 2009
Study Completion
August 1, 2009
Last Updated
July 18, 2016
Record last verified: 2016-07