NCT01313468

Brief Summary

It has been reported that obese individuals are seated 2 ½ hour more than lean individuals and that non exercise thermo genesis (NEAT) may vary with as much as 2000 Kcal/day between equal size people due to different occupational and leisure time activities. The primary aim of the study is to investigate if 10 weeks of exercise training increase NEAT in sedentary men. Subject will be randomized to three different training intervention, with 3 exercise session each week for 10 weeks. NEAT will be measured using an activity sensor and recorded over a 7 day period both before and after training.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2011

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2011

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 10, 2011

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 11, 2011

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2011

Completed
Last Updated

March 30, 2017

Status Verified

March 1, 2017

Enrollment Period

9 months

First QC Date

March 10, 2011

Last Update Submit

March 29, 2017

Conditions

Keywords

NEATmaximal oxygen uptakestroke volume

Outcome Measures

Primary Outcomes (1)

  • nonexercise activity thermogenesis

    NEAT Will be measured using an activity sensor. Physical activity is recorded over a 7 day period. The energy equivalent of each of these activities is determined. The time spent in each activity is then multiplied by equivalent for the activity. The values are then summed to derive an estimate of NEAT.

    Baseline and 10 weeks

Secondary Outcomes (1)

  • Cardiopulmonary maximal oxygen uptake

    Baseline and 10 weeks

Study Arms (3)

4 x 4 Interval

EXPERIMENTAL

4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate separated by 3 minutes of active brakes in between at 70% of maximal heart rate.

Behavioral: 4 x 4 minutes Intervals

1 4 minutes interval

EXPERIMENTAL

1 x 4 minutes intervals at 90-95% of HR max

Behavioral: 1 x 4 minute interval

Moderate continuous Training

EXPERIMENTAL

47 minutes of Moderate continuous Training

Behavioral: Moderate continuous Training

Interventions

1 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate

1 4 minutes interval

4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate separated by 3 minutes of active brakes in between at 70% of maximal heart rate.

4 x 4 Interval

47 minutes of Moderate continuous Training

Moderate continuous Training

Eligibility Criteria

Age18 Years - 50 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Male gender
  • Age 18-50
  • BMI 25-30 kg x m2
  • No significant comorbidities
  • Abel to exercise
  • Not partaking in organized physical activity

You may not qualify if:

  • Inability to exercise due to musculoskeletal conditions
  • Known ischemic cardiovascular disease
  • High daily physical and occupational activity levels

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NTNU

Trondheim, 7491, Norway

Location

Related Publications (1)

  • Zisko N, Stensvold D, Hordnes-Slagsvold K, Rognmo O, Nauman J, Wisloff U, Karlsen T. Effect of Change in VO2max on Daily Total Energy Expenditure in a Cohort of Norwegian Men: A Randomized Pilot Study. Open Cardiovasc Med J. 2015 Apr 30;9:50-7. doi: 10.2174/1874192401509010050. eCollection 2015.

Study Officials

  • Trine Karlsen

    National Taiwan Normal University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 10, 2011

First Posted

March 11, 2011

Study Start

February 1, 2011

Primary Completion

November 1, 2011

Study Completion

November 1, 2011

Last Updated

March 30, 2017

Record last verified: 2017-03

Data Sharing

IPD Sharing
Will not share

Locations