NCT00522561

Brief Summary

Inter-individual variability in energetic cost of running may be partly explained by lower limbs mechanical characteristics. The transposition of muscle mechanical model with two components (contractile and elastic) to the whole lower limb mechanical behavior analysis during running. The main aim of present investigation is to study the effects of lower limb mechanical characteristic (force, velocity, stiffness) on the energetic cost of running using a lower limb mechanical approach including both contractile and elastic components.Twenty healthy men will run on a treadmill at 12km.h-1 in 8 different 5 min-conditions. Through conditions, stride frequency, sole stiffness and subject's body weight will be changed to allow artificial variations in lower limb mechanical characteristics. Energetic and non-invasive mechanical measurements analysis will be performed to obtain energetic cost of running and to compute force, velocity and stiffness of lower limbs for each condition.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Jan 2008

Shorter than P25 for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 28, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 29, 2007

Completed
4 months until next milestone

Study Start

First participant enrolled

January 1, 2008

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2008

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2008

Completed
Last Updated

June 12, 2009

Status Verified

June 1, 2009

Enrollment Period

1 month

First QC Date

August 28, 2007

Last Update Submit

June 9, 2009

Conditions

Keywords

Healthy volunteersrunningenergetic costlimb mechanical characteristicscontractile componentselastic componentshealthy men doing regularly physical activities

Outcome Measures

Primary Outcomes (1)

  • the energetic cost of running: the energetic cost (Oxygen consumption by meter covered) is calculated by the ratio of oxygen consumption on the running velocity.

    within 4 weeks after inclusion

Study Arms (1)

1

OTHER

healthy volunteers

Other: energetic and non invasive limb mechanical measurements

Interventions

Force velocity stiffness running

1

Eligibility Criteria

Age20 Years - 35 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy men being between 20 and 35 years old and doing regularly physical activities
  • subjects must be able to run at 12 km/h during 15 minutes in aerobic condition
  • not be sedentary and not do running competitions
  • be affiliated to a social security system
  • Sign a written inform consent

You may not qualify if:

  • presenting a clinic sign of intolerance to exercise, and particularly to running
  • overweight subjects
  • having a medical treatment which may interfere with the running quality or with one of the physiological parameters measured
  • taking part at the same moment in another medicinal research

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Service de Physiologie clinique et de l'exercice - CHU Saint-Etienne

Saint-Etienne, 42055, France

Location

Study Officials

  • Roger OULLION, MD PhD

    CHU de Saint-Etienne

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 28, 2007

First Posted

August 29, 2007

Study Start

January 1, 2008

Primary Completion

February 1, 2008

Study Completion

March 1, 2008

Last Updated

June 12, 2009

Record last verified: 2009-06

Locations