Quadroiliac Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty

NCT07815145 | Recruiting

• 1 other identifier: 36265PR152/7/26
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate and compare the postoperative analgesic efficacy, opioid consumption, motor function preservation, and quality of recovery of ultrasound-guided Quadroiliac Plane Block (QIPB) versus transmuscular quadratus lumborum block (QLB) in patients undergoing THA under spinal anesthesia.

Conditions

Quadroiliac Plane Block; Transmuscular Quadratus Lumborum Block; Postoperative Analgesia; Total Hip Arthroplasty

Outcome Measures

Primary Outcomes (1)

• Total morphine consumption

  Rescue analgesia of morphine will be given as 3 mg bolus if the numeric rating scale (NRS) \> 3 to be repeated after 30 min if pain persists until the NRS \< 4.

  24 hours postoperatively

Secondary Outcomes (5)

• Degree of pain

  24 hours postoperatively

• Time to the 1st rescue analgesia

  24 hours postoperatively

• Time for ambulation

  24 hours postoperatively

• Length of hospital stay

  Till the discharge from hospital (Up to 2 weeks)

• Incidence of adverse events

  24 hours postoperatively

Study Arms (2)

Group QIP

EXPERIMENTAL

Patients will receive an ultrasound-guided Quadroiliac Plane Block (QIPB) using 20 mL of bupivacaine 0.25%.

Drug: Quadroiliac Plane Block

Group QLB

EXPERIMENTAL

Patients will receive ultrasound-guided quadratus lumborum block (QLB) (transmuscular approach) using 20 mL of 0.25% bupivacaine.

Drug: Transmuscular quadratus lumborum block

Interventions

Quadroiliac Plane Block DRUG

Patients will receive an ultrasound-guided Quadroiliac Plane Block (QIPB) using 20 mL of bupivacaine 0.25%.

Group QIP

Transmuscular quadratus lumborum block DRUG

Patients will receive ultrasound-guided quadratus lumborum block (QLB) (transmuscular approach) using 20 mL of 0.25% bupivacaine.

Group QLB

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18-75 years.
• Both sexes.
• American Society of Anesthesiologists (ASA) classification I-III.
• Scheduled for elective primary unilateral total hip arthroplasty under spinal anesthesia.

You may not qualify if:

• Allergy to local anesthetics.
• Infection at the injection site.
• Coagulopathy or bleeding disorders.
• Neuromuscular disorders.
• Chronic opioid use or dependence.
• Body mass index (BMI) \> 40 kg/m².
• Severe cardiac, hepatic, renal, or respiratory dysfunction.
• Contraindication to regional anesthesia.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, El-Gharbia, 31527, Egypt

RECRUITING

Central Study Contacts

Mohammed S Elsharkawy, MD

CONTACT

00201148207870; mselsharkawy@med.tanta.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Study Record Dates

• First Submitted: September 6, 2026
• First Posted: September 11, 2026
• Study Start: September 12, 2026
• Primary Completion (Estimated): February 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: September 15, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)