Comparison of Epidural and Intravenous Analgesia in Laparoscopic Sleeve Gastrectomy Patients

NCT07712224 | Completed

• 1 other identifier: TrabzonKERH-LSG-2025-01
• Study Type: observational
• Target: 106
• Locations: 1 country
• Sites: 1

Brief Summary

This retrospective observational study aimed to compare the effects of epidural analgesia and intravenous analgesia on early postoperative pulmonary function in patients undergoing laparoscopic sleeve gastrectomy. Preoperative and postoperative pulmonary function tests, pain scores, opioid consumption, and intraoperative respiratory parameters were evaluated.

Conditions

Obesity; Bariatric Surgery; Laparoscopic Sleeve Gastrectomy

Keywords

Epidural Analgesia; Intravenous Analgesia; Pulmonary Function; FEV1; Postoperative Analgesia; Obesity; Bariatric Surgery

Outcome Measures

Primary Outcomes (1)

• Change in FEV1 at 24 Hours After Surgery

  Assessment of postoperative change in forced expiratory volume in 1 second (FEV1) measured before surgery and at postoperative 24 hours.

  Preoperative period and postoperative 24 hours

Study Arms (2)

Epidural Analgesia

Patients who received thoracic epidural analgesia for postoperative pain management after laparoscopic sleeve gastrectomy.

Procedure: Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution)

Intravenous Analgesia

Patients who received intravenous analgesia for postoperative pain management after laparoscopic sleeve gastrectomy.

Drug: Intravenous analgesia

Interventions

Intravenous analgesia DRUG

Intravenous tramadol-based patient-controlled analgesia for postoperative pain management.

Intravenous Analgesia

Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution) PROCEDURE

Thoracic epidural catheter-based analgesia using bupivacaine and fentanyl for postoperative pain management.

Epidural Analgesia

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult obese patients undergoing laparoscopic sleeve gastrectomy at a tertiary training and research hospital.

You may qualify if:

• Adult patients aged 18-65 years
• ASA physical status III
• Undergoing laparoscopic sleeve gastrectomy
• Availability of preoperative and postoperative pulmonary function tests
• Availability of arterial blood gas analysis data
• Receipt of epidural or intravenous postoperative analgesia

You may not qualify if:

• Missing pulmonary function test data
• Incomplete medical records
• Conversion to open surgery
• Severe respiratory disease affecting pulmonary function assessment

Sponsors & Collaborators

• Trabzon Kanuni Education and Research Hospital: lead

Study Sites (1)

Trabzon Kanuni Training and Research Hospital

Trabzon, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Obesity

Interventions

Analgesia, Epidural

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Analgesia; Anesthesia and Analgesia

Study Officials

• esra kongur, M.D

  Trabzon Kanuni Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 14, 2026
• First Posted: July 17, 2026
• Study Start: January 1, 2025
• Primary Completion: October 15, 2025
• Study Completion: October 15, 2025
• Last Updated: July 17, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)