Sarcopenia Indicators After Bariatric Surgery

NCT07717333 | Recruiting

• 1 other identifier: BS-SARC-2026
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate longitudinal changes in sarcopenia-related parameters in patients undergoing bariatric surgery. Obesity and rapid weight loss following bariatric surgery may lead to changes in muscle mass, muscle strength, and physical performance, which are important components of sarcopenia. Participants will be evaluated before bariatric surgery and during postoperative follow-up visits. Muscle thickness will be assessed using ultrasonography of the femoral muscles. Muscle strength and physical performance will be evaluated using handgrip strength, the 5-meter walk test, and the five-times sit-to-stand test. The study aims to investigate the effects of bariatric surgery on muscle function and physical performance over time and to contribute to the early identification of sarcopenia risk in this patient population.

Conditions

Obesity; Sarcopenia; Bariatric Surgery

Outcome Measures

Primary Outcomes (1)

• Change in Femoral Muscle Thickness

  Femoral muscle thickness will be assessed using ultrasonography before bariatric surgery and during postoperative follow-up visits to evaluate longitudinal changes associated with sarcopenia.

  Preoperative baseline, postoperative 1st month, 3rd month, 6th month, and 12th month assessments

Secondary Outcomes (2)

• Change in Handgrip Strength

  Preoperative baseline, postoperative 1st month, 3rd month, 6th month, and 12th month assessments

• Change in Five-Times Sit-to-Stand Test Performance

  Preoperative baseline, postoperative 1st month, 3rd month, 6th month, and 12th month assessments

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients scheduled to undergo bariatric surgery at the study center will be included in this prospective observational study. Participants will be evaluated before surgery and during postoperative follow-up visits to assess longitudinal changes in muscle thickness, muscle strength, and physical performance related to sarcopenia.

You may qualify if:

• Adults aged 18 years and older
• Patients scheduled to undergo bariatric surgery
• Ability to participate in physical performance tests
• Ability to provide written informed consent

You may not qualify if:

• Presence of neurological or musculoskeletal disorders affecting muscle strength or physical performance
• Severe cardiopulmonary disease limiting physical activity
• Active malignancy
• Pregnancy
• Inability to complete study assessments
• Refusal to participate in the study

Sponsors & Collaborators

• Hatice Zehra FERHATLAR: lead

Study Sites (1)

Kanuni Sultan Suleyman Education and Research Hospital

Istanbul, KÜÇÜKÇEKMECE, 34307, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Obesity; Sarcopenia

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical

Central Study Contacts

Hatice Z FERHATLAR

CONTACT

+905367387869; haticezehraferhatlar@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 24, 2026
• First Posted: July 21, 2026
• Study Start: April 10, 2026
• Primary Completion (Estimated): May 30, 2027
• Study Completion (Estimated): June 30, 2027
• Last Updated: July 21, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)