Retrospective Study of Intensive Therapy Pathways in Children With Cerebral Palsy (P'TI-PARCOURS)

NCT07683455 | Not Yet Recruiting

• 1 other identifier: RNIPH-2025-PTI-PARCOURS
• Study Type: observational
• Target: 75
• Locations: 0 countries
• Sites: N/A

Brief Summary

This retrospective single-center study aims to describe the care pathways of children with unilateral cerebral palsy (hemiplegia) who participated in intensive therapy programs (COLHEMI and/or Mini-COLHEMI) at the Centre des Massues since January 2010. The COLHEMI program (launched in 2010, for children aged 6-12) provides 70 hours of intensive motor learning-based therapy over 2 weeks, while the Mini-COLHEMI program (launched in 2020, for children from age 2) provides 30 hours over 2 weeks. The study will describe the immediate and medium-term impact of these programs on bimanual performance (Assisting Hand Assessment, AHA) and individualized goal attainment (Goal Attainment Scaling, GAS), analyze their impact on bimanual developmental trajectories using all available AHA scores, identify characteristics of good responders, and describe parent satisfaction. Approximately 75 patients will be included. Data are collected retrospectively from electronic and paper medical records by an occupational therapist.

Conditions

Cerebral Palsy; Hemiplegia

Keywords

Cerebral Palsy; Unilateral cerebral palsy; Hemiplegia; Intensive therapy; Constraint-induced movement therapy; Bimanual training; HABIT; Assisting Hand Assessment; Goal Attainment Scaling; Pediatric rehabilitation; Care pathway

Outcome Measures

Primary Outcomes (1)

• Structured Description of Care Pathway Including Intensive Therapy

  Structured description of each patient's care pathway, integrating: type (COLHEMI or Mini-COLHEMI) and number of intensive therapy sessions attended; associated medical treatments (botulinum toxin injections - nature, muscles targeted, and timing relative to each intensive therapy episode); associated surgical treatments (nature and timing relative to each intensive therapy episode); and type of regular rehabilitation follow-up (private practice, medico-social, health institution).

  Full care trajectory from first intensive therapy program participation (from January 2010) to June 2026, collected retrospectively.

Secondary Outcomes (6)

• Immediate Impact on Bimanual Performance - Assisting Hand Assessment (AHA)

  AHA score closest to the start of intensive therapy (within 3 months before) compared to AHA score closest to the end of intensive therapy (within 1 month after).

• Immediate Goal Attainment - Goal Attainment Scaling (GAS)

  Assessed immediately after each intensive therapy program.

• Medium-Term Goal Attainment - Goal Attainment Scaling (GAS) at 3 Months

  Assessed 3 months after each intensive therapy program.

• Impact on Bimanual Developmental Trajectory - Longitudinal AHA Scores

  All AHA scores available in the patient's medical record across the full care trajectory (from first available assessment to June 2026).

• Characteristics of Good Responders to Intensive Therapy

  Variables collected at baseline (pre-therapy) and analyzed against response status defined at immediate post-therapy and 3-month assessments.

Study Arms (1)

Children with Unilateral Cerebral Palsy - COLHEMI / Mini-COLHEMI Intensive Therapy

Retrospective cohort of children with unilateral cerebral palsy (hemiplegia) who participated in at least one intensive therapy program at the Centre des Massues between January 2010 and June 2026: the COLHEMI program (for children aged 6-12 years; 70 hours of motor learning-based intensive therapy over 2 weeks combining mCIMT, bimanual training, and goal-oriented therapy) and/or the Mini-COLHEMI program (for children from age 2; 30 hours over 2 weeks of 10 half-day sessions). Participants may have undergone one or multiple sessions of these programs across their care trajectory, and may have received associated medical treatments (botulinum toxin injections) or surgical interventions before or after intensive therapy.

Other: COLHEMI program

Interventions

COLHEMI program OTHER

the COLHEMI program (for children aged 6-12 years; 70 hours of motor learning-based intensive therapy over 2 weeks combining mCIMT, bimanual training, and goal-oriented therapy) and/or the Mini-COLHEMI program (for children from age 2; 30 hours over 2 weeks of 10 half-day sessions)

Children with Unilateral Cerebral Palsy - COLHEMI / Mini-COLHEMI Intensive Therapy

Eligibility Criteria

• Age: 2 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children with unilateral cerebral palsy (hemiplegia) who participated in at least one COLHEMI or Mini-COLHEMI intensive therapy program at the Centre Médico-Chirurgical de Réadaptation des Massues between January 2010 and June 2026, with available pre- and post-program functional assessments in their medical records.

You may qualify if:

• Minor patient (age \< 18 years)
• Unilateral upper limb involvement due to Cerebral Palsy (hemiplegia)
• Having participated in at least one intensive therapy program (COLHEMI and/or Mini-COLHEMI) since program launch in January 2010
• Participation before June 30, 2026
• Followed at the CMCR des Massues
• Parental opposition to medical data processing for research purposes
• Incomplete medical record

Sponsors & Collaborators

• Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française: lead

MeSH Terms

Conditions

Cerebral Palsy; Hemiplegia; Habits

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Paralysis; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Central Study Contacts

Julie Rozaire

CONTACT

+334 72 38 11 43; julie.rozaire@croix-rouge.fr

Rachel Bard-Pondarre

CONTACT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 18, 2026
• First Posted: July 6, 2026
• Study Start (Estimated): September 1, 2026
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): June 1, 2027
• Last Updated: July 6, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share