NCT01214902

Brief Summary

The research objectives are to test the efficacy of a Modified CIMT treatment in babies diagnosed with hemiplegia, treated in a home program, as compared to a control group of babies receiving a parallel home program but with no CIMT.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2011

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 27, 2010

Completed
2 months until next milestone

First Posted

Study publicly available on registry

October 5, 2010

Completed
7 months until next milestone

Study Start

First participant enrolled

May 1, 2011

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
Last Updated

June 21, 2011

Status Verified

June 1, 2010

Enrollment Period

7 months

First QC Date

July 27, 2010

Last Update Submit

June 20, 2011

Conditions

Outcome Measures

Primary Outcomes (1)

  • Assistive Hand Assessment

    Evaluation of the use of the hemiplegic hand as an assiting hand in bilateral activities

    after two months of treatment

Study Arms (2)

Experimental CIMT

EXPERIMENTAL

Two month home program that includes restricting the non hemiplegic hand an hour a day during play

Device: Constraint induced movement therapy (CIMT)

Active Play

ACTIVE COMPARATOR

Two month home program that includes active use of hemiplegic hand during play one hour a day

Behavioral: play

Interventions

soft mitten worn on the non hemiplegic hand

Also known as: Modifide constraint induced movoment therapy
Experimental CIMT
playBEHAVIORAL

play which encourages the use of the hemiplegic hand

Active Play

Eligibility Criteria

Age7 Months - 18 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Babies age 7-18 months diagnosed with Hemiplegic cerebral palsy

You may not qualify if:

  • Epilepsy not treated

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

ShaareZMC

Jerusalem, Israel

RECRUITING

Related Publications (2)

  • Chamudot R, Parush S, Rigbi A, Horovitz R, Gross-Tsur V. Effectiveness of Modified Constraint-Induced Movement Therapy Compared With Bimanual Therapy Home Programs for Infants With Hemiplegia: A Randomized Controlled Trial. Am J Occup Ther. 2018 Nov/Dec;72(6):7206205010p1-7206205010p9. doi: 10.5014/ajot.2018.025981.

  • Chamudot R, Parush S, Rigbi A, Gross-Tsur V. Brain Lesions as a Predictor of Therapeutic Outcomes of Hand Function in Infants With Unilateral Cerebral Palsy. J Child Neurol. 2018 Dec;33(14):918-924. doi: 10.1177/0883073818801632. Epub 2018 Oct 11.

MeSH Terms

Conditions

HemiplegiaCerebral Palsy

Interventions

Constraint Induced Movement TherapyPlay Therapy

Condition Hierarchy (Ancestors)

ParalysisNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsBrain Damage, ChronicBrain DiseasesCentral Nervous System Diseases

Intervention Hierarchy (Ancestors)

Exercise TherapyPhysical Therapy ModalitiesTherapeuticsRehabilitationSensory Art TherapiesComplementary TherapiesPsychotherapyBehavioral Disciplines and Activities

Central Study Contacts

Rena Shara chamudot, Ms.c

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 27, 2010

First Posted

October 5, 2010

Study Start

May 1, 2011

Primary Completion

December 1, 2011

Study Completion

December 1, 2012

Last Updated

June 21, 2011

Record last verified: 2010-06

Locations