The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores

NCT07578545 | Recruiting

• 1 other identifier: 7/24
• Study Type: observational
• Target: 96
• Locations: 1 country
• Sites: 1

Brief Summary

This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing VATS.

Conditions

Thoracic Surgery; Videoassisted Thoracoscopic Surgery,One-lung Ventilation; Regional Anaesthesia; Postoperative Analgesia; Pain Score

Keywords

videoassisted thoracoscopic surgery; regional anaesthesia; postoperative analgesia; chronic pain; quality of recovery

Outcome Measures

Primary Outcomes (1)

• Postoperative opioid consumption

  All patients will receive a standard patient analgesia (PCA) protocol after operation. The postoperative opioid consumption will only be recorded.

  24 hours

Secondary Outcomes (2)

• Postoperative Numerical Rating Scale (NRS) pain scores

  postoperative 24 hours

• Chronic pain

  3 months

Study Arms (3)

Paravertebral block group

Before the surgery, ultrasoud-guided paravertebral block will be performed

Other: Paravertebral block group

İntertransverse process block group

Before the surgery, ultrasoud-guided intertransverse process block will be performed

Other: İntertransverse process block group

Erector spinae plane block group

Before the surgery, ultrasoud-guided erector spinae plane block will be performed

Other: Erector spinae plane block group

Interventions

Paravertebral block group OTHER

Before the surgery, ultrasoud-guided paravertebral block will be performed before the surgery under standart anaesthesia monitoring

Paravertebral block group

Erector spinae plane block group OTHER

Before the surgery, ultrasoud-guided erector spinae plane block will be performed before the surgery under standart anaesthesia monitoring

Erector spinae plane block group

İntertransverse process block group OTHER

Before the surgery, ultrasoud-guided intertransverse process block will be performed before the surgery under standart anaesthesia monitoring

İntertransverse process block group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

It is planned to include ASA score I-III adult patients who are planned to undergo elective VATS

You may qualify if:

• aged 18-75 years
• American Society of Anaesthesiology (ASA) score I-III
• body mass index (BMI) \<35kg/m2
• scheduled for elective VATS

You may not qualify if:

• ASA score ≥4
• BMI ≥35 kg/m2
• declining to give written informed consent
• controendications for block application
• inability to undergo block application
• history neurological disease or peripheral nerve disease
• history of chronic opioid use
• history of severe liver or kidney failure
• patients admitted to the intensive care unit postoperatively intubated

Sponsors & Collaborators

• Antalya Training and Research Hospital: lead

Study Sites (1)

University of Health Sciences, Antalya Training and Research Hospital

Antalya, Muratpaşa, Turkey (Türkiye)

RECRUITING

Related Publications (2)

• Supphapipat K, Samerchua A, Leurcharusmee P, Lapisatepun P, Pipanmekaporn T, Konkarn N, Prapussarakul K, Jinadech T, Wanvoharn M. Single- versus Multiple-Injection Intertransverse Process Block for VATS: A Randomized Trial on Dermatomal Sensory Blockade. J Pain Res. 2025 Sep 15;18:4791-4800. doi: 10.2147/JPR.S545731. eCollection 2025.

  PMID: 40978546 BACKGROUND

• Sandeep B, Huang X, Li Y, Xiong D, Zhu B, Xiao Z. A comparison of regional anesthesia techniques in patients undergoing video-assisted thoracic surgery: A network meta-analysis. Int J Surg. 2022 Sep;105:106840. doi: 10.1016/j.ijsu.2022.106840. Epub 2022 Aug 24.

  PMID: 36030040 BACKGROUND

MeSH Terms

Conditions

Chronic Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Sadik Ozmen

  University of Health Sciences, Antalya Training and Research Hospital

  PRINCIPAL INVESTIGATOR

• Batuhan Kılıc

  University of Health Sciences, Antalya Training and Research Hospital

  PRINCIPAL INVESTIGATOR

• Hacer Boztepe Yesilcay

  University of Health Sciences, Antalya Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Sadik Ozmen

CONTACT

+905324205282; sadikozmen@hotmail.com

Batuhan Kilic

CONTACT

+905319001549

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 21, 2026
• First Posted: May 11, 2026
• Study Start: May 4, 2026
• Primary Completion (Estimated): October 4, 2026
• Study Completion (Estimated): November 4, 2026
• Last Updated: May 11, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)