The Effects of Regional Anaesthesia Techniques on Hemidiaphragm Paralysis, Postoperative Recovery Quality, Opioid Consumption, and Pain Scores

NCT07553611 | Not Yet Recruiting

• 1 other identifier: 4/21
• Study Type: observational
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the effects of ultrasound-guided interscalene, erector spinae plane, costoclavicular, and supraclavicular blocks on hemidiaphragmatic paralysis, postoperative recovery quality, opioid consumption, and pain scores.

Conditions

Regional Anaesthesia; Arthroscopic Shoulder Surgery; Recovery Quality; Opioid Consumption; Postoperative Pain Score; Hemidiaphragmatic Paralysis

Keywords

regional anaesthesia; arthroscopic shoulder surgery; hemidiaphragmatic paralysis; recovery quality; opioid consumption; postoperative pain score

Outcome Measures

Primary Outcomes (1)

• Hemidiaphragmatic paralysis

  Diaghragmatic excursion will be assessed using a real-time M-mode ultrasound during quite breathing, deep breathing, and sniffing maneuvers (deep breathing through the nose)

  30 minutes

Secondary Outcomes (3)

• Recovery quality

  5 minutes

• Postoperative analgesic consumption

  24 hours

• Postoperative pain intensity

  24 hours

Study Arms (4)

İnterscalene group

Before the surgery, ultrasoud-guided interscalene block will be performed

Other: İnterscalene block group

Erector spinae plane block group

Before the surgery, ultrasoud-guided erector spinae plane block will be performed

Other: Erector spinae plane block group

Costoclavicular block group

Before the surgery, ultrasoud-guided costoclavicular block will be performed

Other: Costoclavicular block group

Supraclavicular block group

Before the surgery, ultrasoud-guided supraclavicular block will be performed

Other: Supraclavivular block group

Interventions

İnterscalene block group OTHER

Before the surgery, ultrasoud-guided interscalene block will be performed before the surgery under standart anaesthesia monitoring

İnterscalene group

Erector spinae plane block group OTHER

Before the surgery, ultrasoud-guided erector spinae plane block will be performed before the surgery under standart anaesthesia monitoring

Erector spinae plane block group

Costoclavicular block group OTHER

Before the surgery, ultrasoud-guided costoclavicular block will be performed before the surgery under standart anaesthesia monitoring

Costoclavicular block group

Supraclavivular block group OTHER

Before the surgery, ultrasoud-guided supraclavivular block will be performed before the surgery under standart anaesthesia monitoring

Supraclavicular block group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

It is planned to include ASA score I-III, aged 18-65 years, who are planned to undergo elective arthroscopic surgery

You may qualify if:

• aged 18-65 years
• American Society of Anaesthesiology (ASA) score I-III
• body mass index (BMI) \<30kg/m2
• scheduled for elective arthroscopic surgery

You may not qualify if:

• ASA score ≥4
• BMI ≥30 kg/m2
• declining to give written informed consent
• controendications for block application
• history of mental or neurological disease, severe liver and/or kidney disease
• history of moderate or severe pulmonary disease
• abnormal preoperative chest X-ray findings
• scheduled for emergency surgery

Sponsors & Collaborators

• Antalya Training and Research Hospital: lead

Study Sites (1)

University of Health Sciences, Antalya Training and Research Hospital

Antalya, Muratpaşa, Turkey (Türkiye)

Location

Related Publications (2)

• Shagufta N, Nishant S, Rajnish K, Adil A. Hemidiaphragmatic paralysis following costoclavicular versus supraclavicular brachial plexus block: A systematic review and meta-analysis. J Anaesthesiol Clin Pharmacol. 2025 Oct-Dec;41(4):587-599. doi: 10.4103/joacp.joacp_415_24. Epub 2025 Jul 9.

  PMID: 41181256 BACKGROUND

• Kim DH, Lin Y, Beathe JC, Liu J, Oxendine JA, Haskins SC, Ho MC, Wetmore DS, Allen AA, Wilson L, Garnett C, Memtsoudis SG. Superior Trunk Block: A Phrenic-sparing Alternative to the Interscalene Block: A Randomized Controlled Trial. Anesthesiology. 2019 Sep;131(3):521-533. doi: 10.1097/ALN.0000000000002841.

  PMID: 31283740 BACKGROUND

Study Officials

• Arzu Karaveli

  University of Health Sciences, Antalya Training and Research Hospital

  PRINCIPAL INVESTIGATOR

• Bayram Akdag

  University of Health Sciences, Antalya Training and Research Hospital

  PRINCIPAL INVESTIGATOR

• Fatih Duygun

  University of Health Sciences, Antalya Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Arzu Karaveli

CONTACT

+905325611300; arzukaraveli@hotmail.com

Bayram Akdag

CONTACT

+905427688949; bayramakdag6507@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 21, 2026
• First Posted: April 28, 2026
• Study Start: April 21, 2026
• Primary Completion (Estimated): October 21, 2026
• Study Completion (Estimated): November 21, 2026
• Last Updated: April 28, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)