Comparison of Edge Laminar Block and Serratus Posterior Superior Intercostal Plane Block for Postoperative Pain Management After VATS

NCT07073495 | Completed

• 1 other identifier: 2025-06/84
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to compare the effectiveness of Edge Laminar Block (ELB) and Serratus Posterior Superior Intercostal Plane Block (SPSIPB) in managing postoperative pain after Video-Assisted Thoracoscopic Surgery (VATS). The study will evaluate postoperative pain scores (VAS/NRS), opioid consumption, incidence of postoperative nausea and vomiting (PONV), additional analgesic requirements, and patient satisfaction between the two regional analgesic techniques. This research seeks to provide guidance for optimal postoperative pain management in VATS patients.

Conditions

Postoperative Pain; Thoracic Surgery; Video-assisted Thoracoscopic Surgery (VATS); Serratus Posterior Superior Intercostal Plane Block; Edge Laminar Block

Keywords

Edge Laminar Block (ELB); Serratus Posterior Superior Intercostal Plane Block (SPSIPB); Video-Assisted Thoracoscopic Surgery (VATS); Postoperative Pain; Pain Assessment; Thoracic Surgery; Opioid Sparing; Interfascial Plane Blocks

Outcome Measures

Primary Outcomes (1)

• Postoperative pain intensity measured by Visual Analog Scale (VAS) at rest at 2, 6, 12, and 24 hours after surgery.

  Pain intensity will be assessed using the Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates the worst imaginable pain. The primary outcome is the comparison of VAS scores between the two groups at specified time points.

  2, 6, 12, and 24 hours postoperatively

Secondary Outcomes (3)

• Total opioid consumption (in mg morphine equivalents) within the first 24 hours after surgery

  First 24 hours postoperatively

• Incidence of postoperative complications (e.g., nausea, vomiting, respiratory depression) within 24 hours after surgery.

  First 24 hours postoperatively

• Patient satisfaction with pain management, assessed by a numerical rating scale (1-5) at 24 hours after surgery.

  24 hours postoperatively

Study Arms (2)

ELB Group

Patients undergoing VATS who received Edge Laminar Block (ELB) for postoperative pain management. ELB involves the injection of local anesthetic at the edge of the thoracic lamina as a regional anesthesia technique. The efficacy and safety of ELB will be evaluated in this group.

SPSIPB Group

Patients undergoing VATS who received Serratus Posterior Superior Intercostal Plane Block (SPSIPB) for postoperative pain management. SPSIPB involves the injection of local anesthetic into the intercostal plane beneath the serratus posterior superior muscle. The efficacy and safety of SPSIPB will be evaluated in this group.

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population will consist of adult patients (aged 18-75 years) scheduled for elective video-assisted thoracoscopic surgery (VATS) at \[Your Hospital Name/Institution Name\]. These patients will be categorized based on the regional anesthesia technique received (Edge Laminar Block or Serratus Posterior Superior Intercostal Plane Block) for postoperative pain management. Patients with ASA physical status I-III will be included, ensuring a relatively healthy surgical population.

You may qualify if:

• Adults aged 18-75 years Scheduled for elective video-assisted thoracoscopic surgery (VATS) American Society of Anesthesiologists (ASA) physical status I-III Ability to provide informed consen

You may not qualify if:

• Known allergy or contraindication to local anesthetics Chronic opioid use or chronic pain conditions Coagulopathy or use of anticoagulant therapy Infection at the injection site Severe hepatic or renal dysfunction Pregnancy or breastfeeding Inability to understand or complete pain assessment scales

Sponsors & Collaborators

• Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital: lead

Study Sites (1)

Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital

Ankara, 06, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr. Eda Cennet Caferoğlu

Study Record Dates

• First Submitted: July 10, 2025
• First Posted: July 18, 2025
• Study Start: July 15, 2025
• Primary Completion: October 15, 2025
• Study Completion: December 15, 2025
• Last Updated: February 17, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)