NCT07420842

Brief Summary

Adolescents (N = 700) participated in the online survey-based randomized experiment focused on understanding youth perceptions of e-cigarette influencer marketing on social media. Specifically, the study assessed how age appearance of social media influencers, fitness-related contextual framing of e-cigarette content, and perceived influencer credibility jointly shape adolescent harm perceptions, appeal, and susceptibility to e-cigarette use. Participants were randomly shown 6 videos, featuring younger- or older-looking influencers promoting e-cigarettes in the following experimental conditions: 1) younger-looking influencers promoting e-cigarettes alongside fitness-oriented activities (condition 1); 2) older-looking influencers promoting e-cigarettes alongside fitness-oriented activities (condition 2); 3) younger-looking influencers promoting e-cigarettes without any fitness-oriented content; and 4) older-looking influencers promoting e-cigarettes without any fitness-oriented content (control). After watching each video, participants rated perceptions of influencer credibility (i.e., honesty, trustworthiness, knowledge) on the scale of 0 (e.g., dishonest) to 100 (honest). Among all participants, harm perceptions and appeal of e-cigarettes was also assessed. Susceptibility to use e-cigarettes was assessed among never users of e-cigarettes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
700

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 16, 2025

Completed
16 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2025

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

February 1, 2026

Completed
18 days until next milestone

First Posted

Study publicly available on registry

February 19, 2026

Completed
Last Updated

February 19, 2026

Status Verified

February 1, 2026

Enrollment Period

16 days

First QC Date

February 1, 2026

Last Update Submit

February 11, 2026

Conditions

Outcome Measures

Primary Outcomes (4)

  • Harm Perceptions of e-cigarettes

    Responses to one question adapted from PATH, "Based on the videos you just watched, do you think using e-cigarettes for vaping nicotine is harmful to your health?" The outcome was assessed on the 5-point ordinal scale with the following response choices: Not at all harmful, slightly harmful, somewhat harmful, very harmful, extremely harmful.

    assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment

  • Perceived appeal of e-cigarettes

    Description: Responses to the following questions: using e-cigarette is: not cool/cool, unattractive/attractive were assessed on the 7-point semantic differential scale with the word pairs anchored at each end. The scale was adapted from prior research. The items were combined (by summing all the non-missing values of the items) into one variable (α=0.94).

    Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment

  • Susceptibility to e-cigarette use

    Susceptibility to e-cigarette use was measured (among never-users of e-cigarettes), using the validated three-item scale (indicating peer influence, intention, and curiosity about e-cigarette use) adapted from PATH, and combined into one variable (α=0.93). Consistent with prior research, the measure was dichotomized with responses "definitely not" to all items being coded as "not susceptible" and responses "probably not," "probably yes", or "definitely yes" being coded as "susceptible."

    Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment

  • Perceived influencer credibility

    Perceived influencer credibility (i.e., honesty, trustworthiness, knowledge) were assessed using a 0 (e.g., dishonest) -100 (e.g., honest) scale that has been validated in prior research.

    Assessed six times immediately after each of the six videos during the 15-minute-long survey-based experiment

Study Arms (4)

Videos featuring young influencers promoting e-cigarettes alongside fitness-related activities

EXPERIMENTAL

a 10 second video clip

Other: Youth Perceptions of Influencer Age and Fitness Contexts in E-Cigarette Marketing

Videos featuring older influencers promoting e-cigarettes alongside fitness-related activities

EXPERIMENTAL

a 10 second video clip

Other: Youth Perceptions of Influencer Age and Fitness Contexts in E-Cigarette Marketing

Videos featuring young influencers promoting e-cigarettes without fitness-related activities

EXPERIMENTAL

a 10 second video clip

Other: Youth Perceptions of Influencer Age and Fitness Contexts in E-Cigarette Marketing

Videos featuring older influencers promoting e-cigarettes without fitness-related activities

ACTIVE COMPARATOR

a 10 second video clip

Other: Youth Perceptions of Influencer Age and Fitness Contexts in E-Cigarette Marketing

Interventions

Participants watched online survey-imbedded promotional videos featuring influencers. Influencer age appearance was manipulated using AI-based age filter.

Videos featuring older influencers promoting e-cigarettes alongside fitness-related activitiesVideos featuring older influencers promoting e-cigarettes without fitness-related activitiesVideos featuring young influencers promoting e-cigarettes alongside fitness-related activitiesVideos featuring young influencers promoting e-cigarettes without fitness-related activities

Eligibility Criteria

Age14 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • years of age,
  • English fluency,
  • Current California resident.

You may not qualify if:

  • Not meeting the following criteria:
  • years of age,
  • English fluency,
  • Current California resident.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Qualtrics, survey was administered online

Seattle, Washington, 98101, United States

Location

Related Links

MeSH Terms

Conditions

Vaping

Condition Hierarchy (Ancestors)

SmokingBehavior

Study Officials

  • Jennifer B Unger, PhD

    University of Southern California

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
FACTORIAL
Model Details: Videos featuring young- or older-looking influencers promoting e-cigarettes alongside fitness-related activities or without such activities
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 1, 2026

First Posted

February 19, 2026

Study Start

July 16, 2025

Primary Completion

August 1, 2025

Study Completion

August 1, 2025

Last Updated

February 19, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

survey is anonymous. Data will be publicly available on GitHub repository if a manuscript related to this study is accepted for publication

Locations