NCT07116837

Brief Summary

The purpose of the Aim 2 study is to assess the perceived effectiveness of vaping prevention ads among adolescents and young adults and identify which features of video ads predict perceived message effectiveness. Participants will include adolescents aged 13-17 and young adults aged 18-20 who live in the US and who are susceptible to vaping or who currently vape. In an online survey, participants will be randomized to view five randomly selected vaping prevention ads identified from a previous content analysis. After viewing the videos, participants will rate each video on the perceived message effectiveness scale and respond to questions about vaping appeal and urge to vape. The survey will take 15-20 minutes. A follow-up survey of a subset of participants will be conducted around two weeks after they have been exposed to vaping prevention video ads in the baseline survey. Participants will view a total of six videos, including the five videos they watched previously, shown one at a time, along with one "decoy" video ad. After watching each video ad, participants will indicate whether they remember seeing the ad in the survey they took around two weeks prior. The survey will take 10-15 minutes.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,500

participants targeted

Target at P75+ for not_applicable

Timeline
3mo left

Started Oct 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress75%
Oct 2025Jul 2026

First Submitted

Initial submission to the registry

August 7, 2025

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 12, 2025

Completed
2 months until next milestone

Study Start

First participant enrolled

October 1, 2025

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 18, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 18, 2026

Last Updated

January 28, 2026

Status Verified

January 1, 2026

Enrollment Period

10 months

First QC Date

August 7, 2025

Last Update Submit

January 26, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Perceived Message Effectiveness

    The 3-item perceived message effectiveness scale assesses the extent to which participants perceived the vaping prevention video ads as effective. Response options are on a 5-point scale from 1="Not at all" to 5="A great deal". The overall scale score is determined by averaging scores from the 3 items, with higher scores representing higher perceived message effectiveness. This is the primary outcome for the main study.

    Baseline (Main study)

  • Recognition

    This survey item assesses whether the participant remembers viewing the ad in the baseline survey 2 weeks prior. Response options are "Yes", "No", and "Not sure". The response will be dichotomized as 1 = "Yes" and 0 = "No"/"Not sure" for analyses. This is the primary outcome for the follow-up study.

    Two-week Follow-up

Secondary Outcomes (2)

  • Urge to vape

    Baseline

  • Vaping appeal

    Baseline

Study Arms (1)

Vaping

EXPERIMENTAL

Adolescents and young adults who are susceptible to vaping or currently vape.

Behavioral: Vaping prevention video ads

Interventions

Participants will view and rate 5 vaping prevention video ads. The vaping prevention video ads cover a variety of different topics and were identified in a previous study activity.

Vaping

Eligibility Criteria

Age13 Years - 20 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Age 13-20 years old
  • Current vaper (defined as using e-cigarettes in the past 30 days) or susceptible to vaping. Participants will be considered 'susceptible to vaping' if they answer anything other than "definitely not" to 3 screening items assessing their susceptibility to vaping. An example item is, "If one of your best friends were to offer you a vape, would you use it?" (Definitely not, probably not, probably yes, definitely yes).
  • Live in the United States

You may not qualify if:

  • Live outside of the United States

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of North Carolina, Chapel Hill

Chapel Hill, North Carolina, 27599, United States

RECRUITING

Related Links

MeSH Terms

Conditions

Vaping

Condition Hierarchy (Ancestors)

SmokingBehavior

Study Officials

  • Sarah Kowitt, PhD

    UNC Lineberger Comprehensive Cancer Center

    PRINCIPAL INVESTIGATOR
  • Seth Noar, PhD

    UNC Lineberger Comprehensive Cancer Center

    PRINCIPAL INVESTIGATOR
  • Youjin Jang, PhD

    UNC Lineberger Comprehensive Cancer Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sarah Kowitt, PhD

CONTACT

Seth Noar, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 7, 2025

First Posted

August 12, 2025

Study Start

October 1, 2025

Primary Completion (Estimated)

July 18, 2026

Study Completion (Estimated)

July 18, 2026

Last Updated

January 28, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations