NCT06433466

Brief Summary

Young adults (N = 1,500) will participate in the online survey-based experiment. They will be randomly shown 10 videos, featuring influencers promoting e-cigarettes alongside healthy lifestyle activities (experimental group), or a healthy lifestyle activity alone (control). After watching each video, participants will rate perceptions of influencer credibility (i.e., honesty, trustworthiness, knowledge, attractiveness, intelligence, and popularity) on the scale of 0 (e.g., dishonest) to 100 (honest). Among all participants, harm perceptions of e-cigarettes will be assessed. Susceptibility to use e-cigarettes will be assessed among never users. These outcomes will then be compared among participants who perceived influencers as credible and those who perceived influencers as non-credible.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2023

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2023

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

May 14, 2024

Completed
15 days until next milestone

First Posted

Study publicly available on registry

May 29, 2024

Completed
Last Updated

May 29, 2024

Status Verified

May 1, 2024

Enrollment Period

2 months

First QC Date

May 14, 2024

Last Update Submit

May 22, 2024

Conditions

Outcome Measures

Primary Outcomes (3)

  • harm perceptions of e-cigarettes

    Responses to the question, "Do you think vaping e-cigarettes is harmful to your health?" were measured on a Likert scale, ranging from "definitely yes" (1), "probably yes" (2), to "probably not (3)," "definitely not (4)." The measure represents one validated item from the Population Assessment of Tobacco and Health (PATH).

    one-time assessment after the experimental exposure (immediately post-treatment)

  • Susceptibility to use e-cigarettes

    Susceptibility to use e-cigarettes was measured (among never-users of e-cigarettes), using the validated three-item scale adapted from PATH, and combined into one variable (α=0.93). Consistent with prior research, the measure was dichotomized with responses "definitely not" to all items being coded as "not susceptible" and responses "probably not," "probably yes", or "definitely yes" being coded as "susceptible."

    one-time assessment after the experimental exposure (immediately post-treatment)

  • Perceptions of influencer credibility

    Perceptions of influencer credibility (i.e., honesty, trustworthiness, knowledge, intelligence, attractiveness, and popularity) were assessed using a 0 (e.g., dishonest) -100 (e.g., honest) scale that has been validated in prior research.

    assessed 10 times after each video (during treatment, immediately after each video)

Study Arms (2)

Videos featuring influencers promoting e-cigarettes alongside healthy lifestyle activities

EXPERIMENTAL

Young adults were randomly shown 10 videos, featuring influencers promoting e-cigarettes alongside healthy lifestyle activities (experimental group).

Other: Videos featuring influencers promoting e-cigarettes alongside healthy lifestyle activities

Videos featuring influencers showing healthy lifestyle activities

ACTIVE COMPARATOR

Young adults were randomly shown 10 videos, featuring influencers promoting healthy lifestyle activity alone (control).

Other: Videos featuring influencers promoting e-cigarettes alongside healthy lifestyle activities

Interventions

Young adults were randomly shown 10 videos, featuring influencers promoting e-cigarettes alongside healthy lifestyle activities (experimental group), or a healthy lifestyle activity alone (control).

Videos featuring influencers promoting e-cigarettes alongside healthy lifestyle activitiesVideos featuring influencers showing healthy lifestyle activities

Eligibility Criteria

Age18 Years - 24 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • years of age,
  • English fluency,
  • Current California resident.
  • The survey was sampled to be representative by age group (18 to 24) and gender, and was weighted to be representative by age, gender, race, and educational attainment using propensity score weighting.

You may not qualify if:

  • Not meeting these criteria:
  • years of age,
  • English fluency,
  • Current California resident.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

YouGov, online

Los Angeles, California, 94102, United States

Location

Related Publications (1)

  • Vassey J, Vogel EA, Unger JB, Cho J, Bae D, Donaldson SI, Allem JP. Impact of Instagram and TikTok influencer marketing on perceptions of e-cigarettes and perceptions of influencers in young adults: a randomised survey-based experiment. Tob Control. 2025 Feb 13:tc-2024-059021. doi: 10.1136/tc-2024-059021. Online ahead of print.

MeSH Terms

Conditions

Vaping

Condition Hierarchy (Ancestors)

SmokingBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

May 14, 2024

First Posted

May 29, 2024

Study Start

May 1, 2023

Primary Completion

June 30, 2023

Study Completion

June 30, 2023

Last Updated

May 29, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations