Chewing Under Dual-Tasking in MS

NCT07366216 | Not Yet Recruiting

• 1 other identifier: 1919B012411772
• Study Type: observational
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate the effects of visual, auditory, and motor dual-task conditions on chewing performance in individuals with multiple sclerosis, compared with healthy controls.

Conditions

Multiple Sclerosis

Outcome Measures

Primary Outcomes (5)

• Test of Masticating and Swallowing Solids

  Test of Masticating and Swallowing Solids (TOMASS) is a standardized clinical assessment used to evaluate solid bolus mastication and swallowing performance.

  Baseline (single-task and dual-task conditions assessed on the same day)

• Mini-Mental State Examination (MMSE)

  The MMSE is a brief, widely used screening tool for assessing global cognitive function.

  Baseline

• Go/No-Go Test

  The Go/No-Go Test is a neuropsychological assessment used to evaluate response inhibition and sustained attention.

  Baseline (single-task and dual-task conditions assessed on the same day)

• Auditory Reaction Time Test

  The Auditory Reaction Time Test is used to assess auditory attention and the speed of motor response to auditory stimuli.

  Baseline (single-task and dual-task conditions assessed on the same day)

• Tap Tool

  The Tap Tool is a neuropsychological and motor performance assessment used to evaluate psychomotor speed and fine motor control.

  Baseline (single-task and dual-task conditions assessed on the same day)

Study Arms (2)

Multiple Sclerosis

Healthy Control

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of individuals with multiple sclerosis and age-matched healthy controls.

You may qualify if:

• Individuals aged between 18 and 65 years
• Mini-Mental State Examination (MMSE) score of 24 or higher
• Right-hand dominance

You may not qualify if:

• Presence of visual and/or hearing impairment
• Presence of difficulties in solid food intake and/or complaints related to mastication
• Presence of neurological, psychological, cognitive, and/or chronic conditions that may affect mastication or chewing function
• History of interventions affecting oral structure (e.g., oral/maxillofacial surgery or radiotherapy) within the last month
• Known allergy to the food used in the test

Sponsors & Collaborators

• Ondokuz Mayıs University: lead

Study Sites (1)

Ondokuz Mayis University

Samsun, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Central Study Contacts

Seda Nur Kemer, PhD

CONTACT

+905467861866; sedakemer@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator, PT, PhD

Study Record Dates

• First Submitted: January 9, 2026
• First Posted: January 26, 2026
• Study Start: January 26, 2026
• Primary Completion: February 15, 2026
• Study Completion: March 1, 2026
• Last Updated: January 26, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)