The Effect of Dual Task On Upper Extremity Functions In Multiple Sclerosis Patients

NCT06270342 | Completed DMC

• 1 other identifier: DTMS
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The primary aim of this study was to investigate the effect of dual tasking on upper extremity functions in individuals with multiple sclerosis (MS) and compare with healthy controls. Additionally, another aim of our study was to compare the cognitive status, quality of life, fatigue and emotional states of individuals with MS and healthy controls.

Conditions

Multiple Sclerosis

Keywords

Dual Task; Dual Task Effect; Multiple Sclerosis; Upper Extremity

Outcome Measures

Primary Outcomes (8)

• The Minnesota Manual Dexterity Test

  Upper Extremity Function Evaluation. The Minnesota Manual Dexterity Test basically consists of two subtests, the placement and translation test. Completing the test faster indicates better dexterity.

  30 minutes

• Dual Task Questionnaire

  Dual Task Difficulty Evaluation. The survey consists of 10 items and is scored out of 5 points per question. A higher total score indicates worse dual task performance.

  10 minutes

• Edinburgh Handedness Questionnaire

  Hand Preference Evaluation. The total scoring is between 100 and -100, individuals with more than 40 points are given right hand; Individuals in this score range from 40 to -40 inclusive are recorded as those who use both hands actively, and individuals with scores of -40 points and below are recorded as left-handed.

  10 minutes

• Expanded Disability Status Scale

  Disability Status Evaluation. A score of 0 on the scale indicates normal neurological status, while a score of 10 means MS-related death.

  10 minutes

• Brief International Cognitive Assessment Battery for Multiple Sclerosis

  Cognitive Status Evaluation. BICAMS comprises three tests, the Symbol Digit Modalities Test (SDMT), the learning trials of the California Verbal Learning Test II (CVLT-II), and the Brief Visuospatial Memory Test-Revised (BVMT-R).

  15 minutes

• Beck Depression Scale

  Emotional Status Evaluation. The lowest score that can be obtained from the scale is 0 and the highest score is 63. According to the resulting total score; It results in absence-mild, mild-moderate, moderate-severe or severe.

  10 minutes

• Fatigue Impact Scale

  Fatigue Status Evaluation. Each question receives a score between 0 (no problem) and 4 (maximum problem). The highest score is 160, and higher scores indicate fatigue.

  5 minutes

• Multiple Sclerosis Quality of Life Questionnaire-54

  Quality of Life Status Evaluation. The survey contains 54 questions consisting of 12 sections. Added 18 questions are about; general quality of life (2 items), health stress (4 items), sexual functions and satisfaction (5 items), cognitive functions (4 items), energy (1 item), pain (1 item) and social functions (1 item).

  15 minutes

Study Arms (2)

MS

patients with multiple sclerosis

Other: dual task assessment

Control

healthy volunteers

Other: dual task assessment

Interventions

dual task assessment OTHER

The Minnesota Manual Dexterity Test was used to evaluate the upper extremity function of the participants in single and dual task conditions, and the Dual Task Questionnaire was used to evaluate the difficulties experienced during dual tasks. In the dual-task turning test, in addition to the single-task turning test, they were given a cognitive task, the task of counting the months of the year backwards from December to January. The dual-task turning test was continued by changing hands at the end of each turn until the last disk was turned. Meanwhile, verbal fluency and hand errors made while spinning the disc were recorded.

Control; MS

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients having been diagnosed with MS and healthy volunteers

You may qualify if:

• Having been diagnosed with Multiple Sclerosis for at least 1 year
• Being between the ages of 18-65
• Being at least a primary school graduate
• Volunteering to participate in the study
• EDSS score between 1 and 6.5

You may not qualify if:

• Patients whose Multiple Sclerosis diagnosis is uncertain
• Having additional neurological disease that may affect clinical evaluation
• Having a neurological and/or psychiatric disease that may affect cognitive tests
• Having had an attack in the last 3 months

Sponsors & Collaborators

• Kutahya Health Sciences University: lead

Study Sites (1)

Kutahya Health Sciences University

Kütahya, 43100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asst. Prof.

Study Record Dates

• First Submitted: February 12, 2024
• First Posted: February 21, 2024
• Study Start: June 1, 2023
• Primary Completion: September 1, 2023
• Study Completion: December 15, 2023
• Last Updated: February 21, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)