Metabolic Syndrome and Related Diseases in Healthcare Workers

NCT06543706 | Completed

• 1 other identifier: K2557
• Study Type: observational
• Target: 7,432
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate the incidence and prevalence of metabolic syndrome and metabolism-related diseases among healthcare workers, identify potential risk factors for these diseases, evaluate the control status of these conditions, and explore the significance of annual regular check-ups in improving metabolic-related health outcomes. All data for the study subjects are sourced from anonymized continuous records in hospital physical examinations and medical case files. The study does not involve any interventions. Upon obtaining the study data, researchers will use retrospective analysis methods to identify possible associations between risk factors and diseases.

Conditions

Metabolic Syndrome X; Diabetes Mellitus Type 2; Hypertension; Hyperlipidemia; Obesity; Cardiovascular Diseases; Stroke

Keywords

metabolic syndrome; metabolic related diseases; medical workers

Outcome Measures

Primary Outcomes (1)

• composite endpoint of cardiovascular and cerebrovascular diseases

  The number of hospitalizations due to severe coronary heart disease, stroke, or sudden cardiac death. The outcome is determined if any of the first three discharge diagnoses include acute myocardial infarction, stroke, or sudden cardiac death, or if an emergency coronary stent placement or coronary artery bypass graft surgery is performed during hospitalization.

  through study completion, an average of 5 years

Secondary Outcomes (1)

• new-onset metabolic syndrome

  through study completion, an average of 5 years

Study Arms (1)

the Metabolic Related Diseases in Medical Workers (MRDMW) cohort

The cohort includes all hospital employees who receive annual check-ups.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthcare workers who were working in the hospital, including those who have retired from the hospital

You may qualify if:

• Age ≥18 years
• Healthcare workers who attend annual check-ups at Peking Union Medical College Hospital

You may not qualify if:

• Presence of metabolic syndrome, hypertension, diabetes, coronary heart disease, or stroke at the time of the first physical examination between 2012 and 2022
• Malignant neoplasm
• Uremia
• Liver failure
• Moderate to severe heart failure

Sponsors & Collaborators

• Peking Union Medical College Hospital: lead

Study Sites (1)

Tengda Xu

Beijing, Beijing Municipality, 100730, China

Location

Related Publications (3)

• Strauss M, Lavie CJ, Lippi G, Brzek A, Vollenberg R, Sanchis-Gomar F, Leischik R. A systematic review of prevalence of metabolic syndrome in occupational groups - Does occupation matter in the global epidemic of metabolic syndrome? Prog Cardiovasc Dis. 2022 Nov-Dec;75:69-77. doi: 10.1016/j.pcad.2022.09.003. Epub 2022 Sep 23.

  PMID: 36162483 RESULT

• Liu J, Liu Q, Li Z, Du J, Wang C, Gao Y, Wei Z, Wang J, Shi Y, Su J, Liu Y, Wang P, Xie C, Li G, Shao B, Zhang L. Prevalence of Metabolic Syndrome and Risk Factors Among Chinese Adults: Results from a Population-Based Study - Beijing, China, 2017-2018. China CDC Wkly. 2022 Jul 22;4(29):640-645. doi: 10.46234/ccdcw2022.138.

  PMID: 35919823 RESULT

• Xi B, He D, Hu Y, Zhou D. Prevalence of metabolic syndrome and its influencing factors among the Chinese adults: the China Health and Nutrition Survey in 2009. Prev Med. 2013 Dec;57(6):867-71. doi: 10.1016/j.ypmed.2013.09.023. Epub 2013 Oct 5.

  PMID: 24103567 RESULT

MeSH Terms

Conditions

Metabolic Syndrome; Diabetes Mellitus, Type 2; Hypertension; Hyperlipidemias; Obesity; Cardiovascular Diseases; Stroke

Condition Hierarchy (Ancestors)

Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Diabetes Mellitus; Endocrine System Diseases; Vascular Diseases; Dyslipidemias; Lipid Metabolism Disorders; Overweight; Overnutrition; Nutrition Disorders; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Tengda Xu

  Department of Health, Peking Union Medical College Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 6, 2024
• First Posted: August 9, 2024
• Study Start: November 18, 2022
• Primary Completion: August 7, 2023
• Study Completion: November 10, 2023
• Last Updated: August 9, 2024

Record last verified: 2024-06

Locations

CN (1)