Cohort in Qianwan New District, Ningbo

NCT06387875 | Recruiting DMC

• 1 other identifier: Hangzhou Bay Cohort
• Study Type: observational
• Target: 30,000
• Locations: 1 country
• Sites: 1

Brief Summary

Our objective is to carry out research on prevention and control of noncommunicable chronic diseases, and establish a risk prediction mechanism for chronic diseases to promote early detection, early diagnosis and early treatment of chronic diseases in natural population in Qianwan District of Ningbo, significantly reduce medical costs and extend population life span.

Conditions

Cardiovascular Diseases; Stroke; Non-Communicable Chronic Diseases

Keywords

cohort; natural population; Non-communicable Chronic Disease

Outcome Measures

Primary Outcomes (3)

• death

  Mortality of all-cause disease were calculated by age, gender and area compared by different health management mode.

  4 years

• incidence of cardio-cerebrovascular diseases

  Incidence of Cardiovascular and Cerebrovascular diseases were calculated by age, gender and area compared by different health management mode.

  4 years

• incidence of other non-communicable chronic diseases

  Incidence of other non-communicable chronic diseases were calculated by age, gender and area compared by different health management mode.

  4 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Relying on the manufacturing factories gathered around Hangzhou Bay Hospital, a relatively stable cohort of participants was provided. According to the entry criteria, eligible subjects were selected to be included in the Hangzhou Bay natural population cohort.

You may qualify if:

• \) Local permanent residents aged 18 and above (including residents with household registration, or residents without household registration but with a permanent job);
• \) No serious physical disability, can communicate normally;
• \) Participate voluntarily and sign informed consent.

You may not qualify if:

• \) Temporary resident and floating population;
• \) There are serious health conditions unable to participate in the survey;
• \) Those who are unwilling to accept the follow-up inspection of the project.

Sponsors & Collaborators

• RenJi Hospital: lead
• Ningbo Hangzhou Bay Hospital: collaborator

Study Sites (1)

Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University

Shanghai, China

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

5-10ml of blood, 20ml of urine and 5g of feces were collected (if necessary) according to the chronic non-communicable disease spectrum and clinical testing needs of Qianwan New District of Ningbo; The blood samples and urine were tested for biochemistry, liver and kidney function, blood lipids and electrolytes according to clinical testing requirements, as well as multi-omics indicators as needed.

MeSH Terms

Conditions

Cardiovascular Diseases; Stroke; Noncommunicable Diseases

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Jun Pu, MD, PhD

  Ningbo Hangzhou Bay Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jun Pu, MD, PhD

CONTACT

86-21-68383477; pujun310@hotmail.com

Wei Zhang, PhD

CONTACT

86-13761780922; zhangwei050080@renji.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 18, 2024
• First Posted: April 29, 2024
• Study Start: November 1, 2023
• Primary Completion (Estimated): June 30, 2027
• Study Completion (Estimated): June 30, 2027
• Last Updated: April 29, 2024

Record last verified: 2024-04

Locations

CN (1)