Different Menstrual Cycle in Eating Behavior Following Resistance Exercise

NCT06208475 | Completed

• 1 other identifier: 202303HM002
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to provide insights into how menstrual cycle phases impact appetite responses to resistance exercise in young women. Healthy young women will participate in four trials: the exercise session in the follicular phase, the exercise session in the luteal phase, the control session in the follicular phase, and the control session in the luteal phase. Various measurements will be taken, including subjective appetite perceptions, appetite hormones, food preferences, lactate levels, estradiol levels, progesterone levels, and energy intake.

Conditions

Menstruation; Energy Balance; Appetitive Behavior; Food Reward

Keywords

Early follicular phase; Mid-luteal phase

Outcome Measures

Primary Outcomes (7)

• Subjective appetite

  The appetite perceptions are obtained through a 0-100 mm visual analog scale. The variables assessed include perceptions of hunger (i.e., "How hungry do you feel?"), satisfaction (i.e., "How satisfied do you feel?"), fullness (i.e., "How full do you feel?"), prospective food consumption (i.e., "How much do you think you can eat?"), and nausea (i.e., "How nauseous do you feel?"), with 0 indicating "not at all" and 100 signifying "extremely.".

  4 hours during each study intervention

• Change in acyl-Ghrelin

  acyl-Ghrelin in pg/mL

  4 hours during each study intervention

• Change in total-Ghrelin

  total-Ghrelin in pg/mL

  4 hours during each study intervention

• Change in PYY

  PYY in pg/mL

  4 hours during each study intervention

• Change in active-GLP-1

  active-GLP-1 in pg/mL

  4 hours during each study intervention

• Change in total-GLP-1

  total-GLP-1 in pg/mL

  4 hours during each study intervention

• Change in lactate

  insulin in mmol/L

  4 hours during each study intervention

Secondary Outcomes (11)

• Explicit liking

  4 hours during each study intervention

• Explicit wanting

  4 hours during each study intervention

• Implicit wanting

  4 hours during each study intervention

• Relative preference

  4 hours during each study intervention

• Fat appeal bias

  4 hours during each study intervention

Study Arms (4)

The exercise in the follicular phase (EF)

EXPERIMENTAL

Resistance exercise during the early-follicular phase (approximately during days 1-7 of the menstrual cycle).

Other: Resistance exercise

The exercise in the luteal phase (EL)

EXPERIMENTAL

Resistance exercise during the mid-luteal phase (approximately during days 18-25 of the menstrual cycle).

Other: Resistance exercise

The control in the follicular phase (CF)

NO INTERVENTION

Sit and rest during the early-follicular phase (approximately during days 1-7 of the menstrual cycle).

The control in the luteal phase (CL)

NO INTERVENTION

Sit and rest during the mid-luteal phase (approximately during days 18-25 of the menstrual cycle).

Interventions

Resistance exercise OTHER

Resistance exercises in the following order: squat, bench press, deadlift. Each exercise consisted of 3 sets with 7 repetitions, using a load of 70% 1RM with 120sec of rest between sets.

The exercise in the follicular phase (EF); The exercise in the luteal phase (EL)

Eligibility Criteria

• Age: 20 Years - 30 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age: 20-30
• Healthy female with normal menstruation
• Weight stable for at least 6 months

You may not qualify if:

• Overweight (BMI \> 30 kg/m\^2 or body fat \> 30%)
• Hypertension (\> 140/90 mmHg)
• Cardiovascular disease, cancer or other chronic diseases

Sponsors & Collaborators

• National Taiwan Normal University: lead

Study Sites (1)

National Taiwan Normal University

Taipei, 106, Taiwan

Location

MeSH Terms

Conditions

Appetitive Behavior

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Behavior, Animal; Behavior

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Hung-Wen Liu, Ph.D.

  National Taiwan Normal University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 4, 2024
• First Posted: January 17, 2024
• Study Start: August 1, 2023
• Primary Completion: June 6, 2024
• Study Completion: June 6, 2024
• Last Updated: June 7, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)