Comparative Effects of Action Observation and Motor Imagery on Upper Limb in Chronic Stroke Patients

NCT06108440 | Completed DMC

• 1 other identifier: REC/RCR & AHS/23/0232
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

To Compare effects of action observation and motor imagery training on upper limb function in chronic stroke patients.

Conditions

Stroke; Upper Extremity Paresis; Motor Activity

Keywords

Stroke; Upper Extremity Paresis; Motor Activity

Outcome Measures

Primary Outcomes (2)

• Fugl-Meyer Assessment Upper Extremity (FMA UE):

  Fugl-Meyer Assessment Upper Extremity (FMA UE): FMA UE is a detailed evaluation tool that quantitatively measures motor function, balance, sensation, joint range of motion, and pain in stroke hemiplegic patients

  6 months

• Wolf Motor Function Test (WMFT):

  Wolf Motor Function Test (WMFT): The Wolf motor function test is a tool to evaluate upper extremity motor function in hemiplegic patients. It has 17 tasks with a score range from 0-5. The inter-rater reliability of the function score is 0.88 and the inter-rated reliability of performance time is 0.97

  6 months

Study Arms (2)

action observation training group

EXPERIMENTAL

Patients in Group A will receive action observation training with conventional treatment.

Other: action observation training

motor imagery training group

ACTIVE COMPARATOR

Patients in Group B will receive motor imagery with conventional treatment.

Other: motor imagery training

Interventions

action observation training OTHER

Patients in Group A will receive action observation training with conventional treatment. All participants will undergo the training for 25 minutes per session, 5 days per week for 8 weeks.

action observation training group

motor imagery training OTHER

Patients in Group B will receive motor imagery with conventional treatment. All participants will receive interventions for twenty-five minutes per session, five times a week, for eight weeks.

motor imagery training group

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Diagnosed with chronic stroke by a neurologist
• months post stroke
• Score 1+ on modified ashworth scale
• Having a score of 24 or higher in the Mini-Mental State Examination

You may not qualify if:

• Patient with neurological condition other than stroke e.g. Parkinson's or multiple sclerosis
• Presence of an attached artificial pacemaker
• Presence of a metal implant in the brain
• Presence of visual impairment
• Presence of unilateral neglect in Line bisection test (25)
• Use of antipsychotic drugs

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Riphah International University

Lahore, Fedral, 44000, Pakistan

Location

Related Publications (4)

• Demartino AM, Rodrigues LC, Gomes RP, Michaelsen SM. Hand function and type of grasp used by chronic stroke individuals in actual environment. Top Stroke Rehabil. 2019 May;26(4):247-254. doi: 10.1080/10749357.2019.1591037. Epub 2019 Mar 23.

  PMID: 30907287 BACKGROUND

• Veldema J, Nowak DA, Gharabaghi A. Resting motor threshold in the course of hand motor recovery after stroke: a systematic review. J Neuroeng Rehabil. 2021 Nov 3;18(1):158. doi: 10.1186/s12984-021-00947-8.

  PMID: 34732203 BACKGROUND

• Kuriakose D, Xiao Z. Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives. Int J Mol Sci. 2020 Oct 15;21(20):7609. doi: 10.3390/ijms21207609.

  PMID: 33076218 BACKGROUND

• Serlin Y, Shelef I, Knyazer B, Friedman A. Anatomy and physiology of the blood-brain barrier. Semin Cell Dev Biol. 2015 Feb;38:2-6. doi: 10.1016/j.semcdb.2015.01.002. Epub 2015 Feb 11.

  PMID: 25681530 BACKGROUND

MeSH Terms

Conditions

Stroke; Paresis; Motor Activity

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• Zeest Hashmi, MSNMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Patients will be divided into Group A (n = 20) and Group B (n = 20) using a randomization through computer generated numbers program. Patients in Group A will receive action observation training with conventional treatment. All participants will undergo the training for 25 minutes per session, 5 days per week for 8 weeks. Patients in Group B will receive motor imagery with conventional treatment. All participants will receive interventions for twenty-five minutes per session, five times a week, for eight weeks.

Study Record Dates

• First Submitted: October 25, 2023
• First Posted: October 31, 2023
• Study Start: August 3, 2023
• Primary Completion: February 1, 2024
• Study Completion: February 1, 2024
• Last Updated: March 15, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)