Action Observation Treatment on Motor Function in Upper Limb of Patients With Chronic Stroke

NCT05084820 | Completed DMC

• 1 other identifier: REC/Lhr/20/0213 Hira Rehman
• Study Type: interventional
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

To determine the effects of action observation treatment on motor functions in upper limb of patients with chronic stroke

Conditions

Stroke

Keywords

stroke; action observation treatment

Outcome Measures

Primary Outcomes (2)

• modified barthal index

  The Modified Barthel Index score was used for practical evaluation in activities of daily living. The MBI comprises of 10 items, 6 out of 10 items scored from 0-2 points, 2 items scored from 0-3 points and other 2 items scored from 0-3 points, giving a highest total score of 20 points.

  40 minutes

• Fugl-Meyer Assessment test

  Fugl-Meyer Assessment test for Upper extermity.to assess level of motor impairment and its recovery after treatment. The FMA-UE comprises of 7 times.

  40 minutes

Study Arms (2)

Action observation treatment

EXPERIMENTAL

Action observation treatment

Combination Product: Action observation treatment

conventional treatment

ACTIVE COMPARATOR

conventional treatment

Combination Product: conventional treatment

Interventions

Action observation treatment COMBINATION_PRODUCT

Participants will watch 5 videos of motor tasks; each video is of 30 sec and watch for 4 times (i.e. for 2 minutes). Then patient will execute the motor act, soon after the observation with an affected limb for 2 minutes, with total rest time of 5 minutes for this treatment. Conventional treatment of muscle stretching, strengthening and ROM exercises will be given for 15 minutes including rest. Total treatment time is 40 minutes.

Action observation treatment

conventional treatment COMBINATION_PRODUCT

conventional treatment of 40 minutes in total will be performed including Stretching (for 8-10 sec with set of 5 repetitions/ session on each side for 3 minutes total with rest), strengthening (weighted bicep curls, side arm raise and open arm movement exercises with set of 5 repetitions/ session for 9 minutes total with rest), Range of motion exercises active and passive with set of 5 repetitions/ session for 3 minutes total with rest and gripping,reaching, grasping exercises (on each side for total 25 minutes including rest) with assistance of physiotherapist

conventional treatment

Eligibility Criteria

• Age: 50 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Chronic Stroke patients (with more than 6 months- 4 years) illness
• Patients that were able to communicate and comprehend oral instructions
• Patients with Mini Mental State Examination (MMSE) score more than 24

You may not qualify if:

• Patients having psychiatric histories.
• Visual and hearing impaired patients
• Patients with speech impairment
• Patients with arthritic deformities in upper limb (with or without using assistive device)
• Patients with diagnosed mental illness.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Riphah international university

Islamabad, Fedral, 44000, Pakistan

Location

Related Publications (4)

• Mao H, Li Y, Tang L, Chen Y, Ni J, Liu L, Shan C. Effects of mirror neuron system-based training on rehabilitation of stroke patients. Brain Behav. 2020 Aug;10(8):e01729. doi: 10.1002/brb3.1729. Epub 2020 Jul 1.

  PMID: 32608554 BACKGROUND

• Keller J, Stetkarova I, Macri V, Kuhn S, Petioky J, Gualeni S, Simmons capital ES, CyrillicD, Arthanat S, Zilber P. Virtual reality-based treatment for regaining upper extremity function induces cortex grey matter changes in persons with acquired brain injury. J Neuroeng Rehabil. 2020 Sep 12;17(1):127. doi: 10.1186/s12984-020-00754-7.

  PMID: 32919473 BACKGROUND

• Keci A, Tani K, Xhema J. Role of Rehabilitation in Neural Plasticity. Open Access Maced J Med Sci. 2019 May 14;7(9):1540-1547. doi: 10.3889/oamjms.2019.295. eCollection 2019 May 15.

  PMID: 31198470 BACKGROUND

• Habibi-Koolaee M, Shahmoradi L, Niakan Kalhori SR, Ghannadan H, Younesi E. Prevalence of Stroke Risk Factors and Their Distribution Based on Stroke Subtypes in Gorgan: A Retrospective Hospital-Based Study-2015-2016. Neurol Res Int. 2018 Jul 26;2018:2709654. doi: 10.1155/2018/2709654. eCollection 2018.

  PMID: 30147952 BACKGROUND

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• zeest hashmi, MS NMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: each participant will be requested to draw either number one or two from a box.number one refers to group A and number two refers to group B. Group A patients will receive conventional treatment of 40 minutes in total. group B is experimental group , patients will watch videos of 5 common motor tasks that implicit the usage of items to be used for action observation treatment.

Study Record Dates

• First Submitted: October 7, 2021
• First Posted: October 20, 2021
• Study Start: October 15, 2020
• Primary Completion: July 15, 2021
• Study Completion: August 15, 2021
• Last Updated: October 20, 2021

Record last verified: 2021-10

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)