Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients

NCT06397170 | Completed DMC

• 1 other identifier: REC/RCR & AHS/23/0281
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

To determine effects of graded repetitive arm supplementary program versus Task based training on Upper limb function in stroke patients.

Conditions

Stroke; Upper Extremity Paresis; Motor Activity

Keywords

Stroke; Upper Extremity Paresis; Motor Activity

Outcome Measures

Primary Outcomes (2)

• Fugl Mayer assessment scale

  It is designed to assess reflex activity, movement control and muscle strength in the upper extremity of people with post-stroke hemiplegia. total score is 126.This tool has an excellent Inter- and intrarater reliability (intra class correlation coefficient = 0.98-0.99), validity is also excellent (r = 0.74-0.93, P \< .0001). Higher scores indicate maximum recovery. higher the score greater is the improvement

  6 months

• The Motor Activity Log (MAL)

  The Motor Activity Log (MAL) is a subjective outcome measure of an individual's real life functional upper limb performance. The Motor activity log is administered by semi-structured interview and items are scored by patients according to their performance of each task over the past 7 days. The MAL adopts a 6-point ordinal scale, although patients can attribute a half-score, resulting in 11-point Likert scales with specified anchoring definitions at 6 points. higher the score greater is the improvement

  6 months

Study Arms (2)

Graded repetitive arm supplementary program group

EXPERIMENTAL

Patients in Group A will receive Graded repetitive arm supplementary program.

Other: Graded repetitive arm supplementary program

Task based training group

ACTIVE COMPARATOR

Patients in Group B will receive Task based training.

Other: Task based training

Interventions

Graded repetitive arm supplementary program OTHER

Patients in Group A will receive Graded repetitive arm supplementary program

Graded repetitive arm supplementary program group

Task based training OTHER

Patients in Group B will receive Task based training.

Task based training group

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with Sub acute stage of stroke.
• Patients with Ischemic and Haemorrhagic stroke.
• Patients with Cognition level on Mini Mental State Examination must be \> 24
• Patients with mild pain in upper extremity according to Numeric Pain Rating Scale
• Patients with Grade 2 active movements in affected extremity Tone of upper limb at Modified Ashworth Scale Grade 1+.

You may not qualify if:

• Other neurological disorders e.g. brain tumor, encephalitis, meningitis, brain abscess.
• Use of antipsychotics
• Use of drugs for spasticity.
• Patients with vestibular impairment.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Imran International Amjad

Islamabad, Punjab Province, 44000, Pakistan

Location

Related Publications (4)

• Connell LA, McMahon NE, Watkins CL, Eng JJ. Therapists' use of the Graded Repetitive Arm Supplementary Program (GRASP) intervention: a practice implementation survey study. Phys Ther. 2014 May;94(5):632-43. doi: 10.2522/ptj.20130240. Epub 2014 Feb 6.

  PMID: 24505098 BACKGROUND

• Veerbeek JM, van Wegen E, van Peppen R, van der Wees PJ, Hendriks E, Rietberg M, Kwakkel G. What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. PLoS One. 2014 Feb 4;9(2):e87987. doi: 10.1371/journal.pone.0087987. eCollection 2014.

  PMID: 24505342 BACKGROUND

• Yang CL, Waterson S, Eng JJ. Implementation and Evaluation of the Virtual Graded Repetitive Arm Supplementary Program (GRASP) for Individuals With Stroke During the COVID-19 Pandemic and Beyond. Phys Ther. 2021 Jun 1;101(6):pzab083. doi: 10.1093/ptj/pzab083.

  PMID: 33682872 BACKGROUND

• Lee HS, Lim JH, Jeon BH, Song CS. Non-immersive Virtual Reality Rehabilitation Applied to a Task-oriented Approach for Stroke Patients: A Randomized Controlled Trial. Restor Neurol Neurosci. 2020;38(2):165-172. doi: 10.3233/RNN-190975.

  PMID: 32176674 BACKGROUND

MeSH Terms

Conditions

Stroke; Paresis; Motor Activity

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• Zeest hashmi

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Patients will be divided into Group A (N=19) will receive Graded repetitive arm supplementary program and Patients in Group B (N=19)will receive Task based training.

Study Record Dates

• First Submitted: April 29, 2024
• First Posted: May 2, 2024
• Study Start: May 1, 2024
• Primary Completion: September 1, 2024
• Study Completion: September 1, 2024
• Last Updated: September 19, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)