The Activation and Walking Speed of the Prefrontal Cortex of the Elderly Mild Cognitive Impairment During Dual Task.

NCT05885867 | Completed

• 1 other identifier: SYU 2023-02-013-002
• Study Type: observational
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to compare to investigate the effect of dual task performance on straight and curved walking in elderly people with mild cognitive impairment. The main question\[s\] it aims to answer are:

• The purpose of this study was to investigate the effect of dual task performance on the activity of the prefrontal cortex in the elderly with mild cognitive impairment during straight and curved walking.
• The purpose of this study was to investigate the effect of dual task performance on gait speed during straight and curved walking in elderly people with mild cognitive impairment. Participants will: For mild cognitive impairment 65 and older who can do dual tasks.
• single task (motor task) : an exercise task, which will perform a 10-meter walking test and a figure-eight walking test.
• double task (motor task + cognitive task) : planned to perform a motor task and a cognitive task together. The cognitive task is scheduled to be a simple calculation problem so that it can be performed without great difficulty while walking.

Conditions

Mild Cognitive Impairment; Dual Task

Outcome Measures

Primary Outcomes (2)

• prefrontal cortex activity for single and dual tasks

  functional near-infrared spectroscopy : fNIRS, a non-invasive vascular-based neuroimaging technology, is a tool that uses light sources and photoreceptors to measure changes in the concentration of oxyhemoglobin (HbO2) in the cerebral cortex area due to the regulation of neural activity. In this study, fNIRS measurements were performed by a wireless cw system (NIRSIT, OBELAB, Republic of Korea) an fNIRS device consisting of five double wavelength (780/850 nm) laser sources and seven detectors. The amount of HbO₂ change while performing the task were measured. The device consists of 15 channels with a distance of 30 mm between each pair.

  through study completion, an average of 1 week.

• Walking speed for single and dual tasks

  Using a stopwatch, real-time measurements will be made in the remaining sections except for the front and back 2m, considering acceleration and deceleration when walking along a straight 14m path and a curved path.

  through study completion, an average of 1 week.

Interventions

Seniors with mild cognitive impairment over 65 years of age BEHAVIORAL

A total of 30 subjects will perform four tasks per person for a single task (motor task) and a double task (motor task + cognitive task), and the test order will be randomly assigned. The subject's prefrontal cortex activity will be measured using fNIRS (NIRSIT, OBELAB). The single task will be to perform a 10-meter walk test and an 8-way walk test as exercise tasks. as not affected by acceleration and deceleration. The dual task will be carried out together with the exercise task and the cognitive task. The cognitive task will be a simple calculation problem so that it can be performed without much difficulty when walking.Subjects will perform a total of three iterations and have a break of 20 seconds before each task begins.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

For mild cognitive impairment 65 and older who can do dual tasks.

You may qualify if:

• A person with a Korean version of the Simplified Mental Status Test (K-MMSE-2) score of 18-23.
• A person who can walk using an auxiliary device.

You may not qualify if:

• A person who cannot walk 3 meters back and forth or stand up from a sitting position
• A person sensitive to infrared lasers
• A person with impaired vision and hearing

Sponsors & Collaborators

• Sahmyook University: lead

Study Sites (1)

Sahmyook university

Seoul, Nowon-gu, 01795, South Korea

Location

MeSH Terms

Conditions

Cognitive Dysfunction

Interventions

Aging

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Growth and Development; Physiological Phenomena

Study Officials

• YuMin Lee, MS candidate

  Sahmyook University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 2 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physical Therapist

Study Record Dates

• First Submitted: April 26, 2023
• First Posted: June 2, 2023
• Study Start: May 31, 2023
• Primary Completion: June 5, 2023
• Study Completion: June 5, 2023
• Last Updated: September 6, 2023

Record last verified: 2023-09

Locations

KR (1)