Effects of Single and Dual Task Training in Individuals With Mild Cognitive Impairment

NCT04301960 | Completed

• 1 other identifier: 2019/23-11
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to compare the effects of single and dual-task training on processing speed, cognitive functions, walking speed, dual-task performance and balance functions in individuals with mild cognitive impairment.

Conditions

Mild Cognitive Impairment

Keywords

Single-task; Dual-task; Processing Speed; Cognitive Functions; Walking Speed; Balance Function

Outcome Measures

Primary Outcomes (1)

• Choice Stepping Reaction Time Test (CSRT)

  A custom-made Choice Stepping Reaction Time step pad (CSRT-MAT) and a computer unit will be used to evaluate the processing speed. The system is consisted of a CSRT-MAT having pressure-sensitive panels and a display monitor connected to a computer unit. The computer unit recorded the timing of foot lift and landing. The step direction is indicated by one arrow changing its color. The CSRT device included 2 tests: Stepping Reaction Time (SRT) and Stroop Test (ST). In this study, only the SRT test will be done. In the SRT test, the participants are asked to step as quickly as possible onto the corresponding arrow on the CSRT-MAT and then return to the center. The reaction time (RT) measured from stimulus occurrence to movement initiation (lift off), movement time (MT) measured from movement initiation to step finalization (step down) and total response time (RsT) measured as the sum of RT and MT.

  8 weeks

Secondary Outcomes (8)

• Stroop Test

  8 weeks

• Verbal Fluency Test (VFT)

  8 weeks

• Serial Subtraction Test (SST)

  8 weeks

• 10 Meter Walking Test (10 MWT)

  8 weeks

• 10 Meter Walking Test with Verbal Fluency Test (10 MWT-VFT)

  8 weeks

Study Arms (2)

Single task group

EXPERIMENTAL

The single task group includes balance gaining and cognitive training. The single task group will have 30-40 minutes of single-task training for 3 sessions per week for 8 weeks.

Other: Single task training

Dual-task

EXPERIMENTAL

The dual-task group includes CSRT Mat training. The dual-task group will have CSRT Mat training for 30-40 minutes of dual-task training for 3 sessions per week for 8 weeks.

Other: Dual task training

Interventions

Single task training OTHER

The single task group includes balance gaining and cognitive training. The single task group will have 30-40 minutes of single-task training for 3 sessions per week for 8 weeks.

Single task group

Dual task training OTHER

The dual-task group includes CSRT Mat training. The dual-task group will have CSRT Mat training for 30-40 minutes of dual-task training for 3 sessions per week for 8 weeks.

Dual-task

Eligibility Criteria

• Age: 65 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Participants who are between 65-85 years of age,
• Who has the Montreal Cognitive Assessment score between 13-26,
• Who has the Quick Mild Cognitive Impairment screen score between 48-67,
• Who has Instrumental Activities of Daily Living Scale score ≥6/8,
• Who says yes to "Do you have a memory problem?" question,
• Who can walk independently without using any walking aids and
• Who is likely to have mild cognitive impairment as a result of the tests will be referred to the neurologist and those whose diagnosis is confirmed will be included in this study.

You may not qualify if:

• Participants who have any musculoskeletal disorders that may cause balance and gait disorders,
• Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies),
• Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance,
• Who has daltonism and
• Who attends any exercise program will not be included in this study.

Sponsors & Collaborators

• Eastern Mediterranean University: lead

Study Sites (1)

Eastern Mediterranean University

Famagusta, Eyalet/Yerleşke, 99450, Cyprus

Location

Related Publications (4)

• Schoene D, Delbaere K, Lord SR. Impaired Response Selection During Stepping Predicts Falls in Older People-A Cohort Study. J Am Med Dir Assoc. 2017 Aug 1;18(8):719-725. doi: 10.1016/j.jamda.2017.03.010. Epub 2017 May 16.

  PMID: 28526585 BACKGROUND

• Faria CA, Alves HVD, Charchat-Fichman H. The most frequently used tests for assessing executive functions in aging. Dement Neuropsychol. 2015 Apr-Jun;9(2):149-155. doi: 10.1590/1980-57642015DN92000009.

  PMID: 29213956 BACKGROUND

• Iyigun G, Kirmizigil B, Angin E, Oksuz S, Can F, Eker L, Rose DJ. The reliability and validity of the Turkish version of Fullerton Advanced Balance (FAB-T) scale. Arch Gerontol Geriatr. 2018 Sep-Oct;78:38-44. doi: 10.1016/j.archger.2018.05.022. Epub 2018 Jun 4.

  PMID: 29886283 BACKGROUND

• Bilgin BF, Iyigun G. Multitask Versus Multicomponent Training on Cognitive and Motor Functions in Persons With Mild Cognitive Impairment: A Randomized Trial. J Aging Phys Act. 2022 Apr 20;30(6):1024-1037. doi: 10.1123/japa.2021-0408. Print 2022 Dec 1.

  PMID: 35453122 DERIVED

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Officials

• Betül Fatma Bilgin, PT

  Eastern Mediterranean University

  PRINCIPAL INVESTIGATOR

• Gözde İyigün, PhD

  Eastern Mediterranean University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research assistant

Model Details: Randomized Controlled Study

Study Record Dates

• First Submitted: March 6, 2020
• First Posted: March 10, 2020
• Study Start: February 16, 2021
• Primary Completion: June 16, 2021
• Study Completion: June 16, 2021
• Last Updated: June 18, 2021

Record last verified: 2021-06

Locations

CY (1)