NCT05634161

Brief Summary

Usability study of software application that provide digitized cognitive intervention therapy for cognitively impaired patients.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Nov 2022

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 21, 2022

Completed
Same day until next milestone

Study Start

First participant enrolled

November 21, 2022

Completed
11 days until next milestone

First Posted

Study publicly available on registry

December 2, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 20, 2023

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2024

Completed
Last Updated

February 9, 2024

Status Verified

February 1, 2024

Enrollment Period

4 months

First QC Date

November 21, 2022

Last Update Submit

February 7, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Usability: Based on scenarios

    Single-point evaluation (baseline)

Secondary Outcomes (6)

  • Usability: Based on user survey

    Single-point evaluation (baseline)

  • Usability: Based on hemodynamic responses

    Single-point evaluation (baseline)

  • Changes in Adas-cog

    After 12 weeks of system usage

  • Changes in ADCS-ADL

    After 12 weeks of system usage

  • Changes in self-reported quality of life

    After 12 weeks of system usage

  • +1 more secondary outcomes

Other Outcomes (1)

  • MMSE

    Single-point evaluation (baseline)

Study Arms (1)

Cognitive Improvement software

Usability assessment of cognitive improvement software

Other: Cognitive improvement software

Interventions

Cognitive improvement software

Cognitive Improvement software

Eligibility Criteria

Age55 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Cognitively Impaired patients aged 55 to 85, based in South Korea.

You may qualify if:

  • Male and Female patients, 55\~85 years
  • Adequate vision, hearing and speaking for neuropsychological testing
  • No difficulty in using mobile application using smartphone
  • Patients with subjective memory complaints, confirmed by informants
  • Cognitive impairment of SD 1 or greater from the age-adjusted normal range in Memory domain in CERAD-NP battery
  • Global CDR 0.5 \~ 1
  • Korean speaker
  • Have an identified trial partner
  • All subjects signed written consent

You may not qualify if:

  • Those unable to provide consent
  • History of transient ischemic attack, stroke, brain tumor
  • History of diagnosis of major depression
  • Symptoms that may interfere with the subject's testing procedure
  • Cerebral hemorrhage
  • Central nervous system infections
  • Prohibited concomitant medication
  • Known or suspected history of drug or alcohol abuse

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul Metropolitan Government Seoul National University Boramae Medical Center

Seoul, 156-707, South Korea

Location

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition DisordersNeurocognitive DisordersMental Disorders

Study Officials

  • Jun-Young Lee, M.D., Ph.D.

    Department of Psychiatry, Seoul National University College of Medicine, Department of Psychiatry, SMG-SNU Boramae Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 21, 2022

First Posted

December 2, 2022

Study Start

November 21, 2022

Primary Completion

March 20, 2023

Study Completion

March 31, 2024

Last Updated

February 9, 2024

Record last verified: 2024-02

Locations