Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

182 trials with published results (15%)

Research Maturity

615 completed trials (50% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

4.1%

51 terminated out of 1232 trials

Success Rate

92.3%

+5.8% vs benchmark

Late-Stage Pipeline

4%

52 trials in Phase 3/4

Results Transparency

30%

182 of 615 completed with results

Key Signals

182 with results92% success51 terminated

Data Visualizations

Phase Distribution

967Total
Not Applicable (720)
Early P 1 (12)
P 1 (68)
P 2 (115)
P 3 (14)
P 4 (38)

Trial Status

Completed615
Unknown194
Recruiting186
Active Not Recruiting76
Not Yet Recruiting60
Terminated51

Trial Success Rate

92.3%

Benchmark: 86.6%

Based on 615 completed trials

Clinical Trials (1232)

Showing 20 of 20 trials
NCT07169630Phase 1Recruiting

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

NCT06130735Not ApplicableActive Not Recruiting

Impact of Intensive Computerized Cognitive Training

NCT07497334Not ApplicableRecruiting

A Novel Multi-Modal Approach to Promote Functional Outcomes in Cognitively Frail Older Adults

NCT05617014Enrolling By InvitationPrimary

Alzheimer's Disease Neuroimaging Initiative 4

NCT07846566Not ApplicableNot Yet Recruiting

Choose Myself (Before) Losing Myself

NCT03954899Not ApplicableRecruitingPrimary

Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

NCT05999929Not ApplicableRecruitingPrimary

Memory Support System Feasibility Study

NCT07839286Not ApplicableNot Yet Recruiting

Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related Dementias

NCT06432166Phase 1Not Yet Recruiting

2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients

NCT07836114Not ApplicableNot Yet Recruiting

Virtual Outreach and Individualized Coaching Extension

NCT07834528Not ApplicableNot Yet Recruiting

Brain Heath Service for Prevention of AD

NCT03649724Phase 2Completed

The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's

NCT07602283Not ApplicableRecruiting

Music for Pain and Dementia

NCT07243600Not ApplicableRecruitingPrimary

Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment

NCT07799402RecruitingPrimary

Microbiome in Aging of Gut and Brain

NCT05375513Not ApplicableRecruitingPrimary

SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@Home)

NCT07149038Not ApplicableActive Not Recruiting

Evaluation of Cerogrin for Auricular Vagus Nerve Stimulation in Vascular Dementia or Vascular Mild Cognitive Impairment

NCT07827963Not Yet Recruiting

VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and Parkinsonism

NCT04396873Phase 1Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

NCT05469360Phase 1Active Not Recruiting

Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants

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