Efficacy of the Cognitive Training Based on Location Information and Activity in People With Mild Cognitive Impairment

NCT03928613 | Completed DMC

• 1 other identifier: B-1903-526-301
• Study Type: interventional
• Target: 43
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to examine therapeutic efficacy of cognitive Training based on location information and activity in people with mild cognitive impairment

Conditions

Mild Cognitive Impairment

Keywords

Cognitive training; Cognitive intervention; Cognitive rehabilitation

Outcome Measures

Primary Outcomes (1)

• Change in CERAD-TS1 score

  Total Score of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Neuropsychological Assessment Battery (CERAD-TS1) . CERAD-TS1 is generated by simply summing the scores of six tests including the 1) Verbal fluency (range 0-24), 2) Boston naming test (0-15), 3) Word List Memory (0-30), 4) Word List Recall (0-10), 5) Word list recognition (0-10), 6) Constructional Praxis (0-11). The range of CERAD-TS1 score is 0 to 100 points), and the higher score represents the better cognitive function.

  baseline and 6 weeks

Secondary Outcomes (3)

• Change in MMSE score

  baseline and 6 weeks

• Change in SMCQ score

  baseline and 6 weeks

• Change in GDS score

  baseline and 6 weeks

Study Arms (1)

Mild Cognitive Impairment

EXPERIMENTAL

* Clinical dementia rating 0 or 0.5 * Diagnosed by physicians as mild cognitive impairment according to the criteria of International Working Group on Mild Cognitive Impairment

Behavioral: tablet based Cognitive Training based on location information

Interventions

tablet based Cognitive Training based on location information BEHAVIORAL

Participants perform Tablet based Cognitive training using interactive voice services and tags three times (minimum 30 minutes per time) a week for 6 weeks

Mild Cognitive Impairment

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged above 60
• Confirmed literacy o Diagnosed with mild cognitive impairment by International Working Group on Mild Cognitive Impairment and Clinical Dementia Rating(CDR) of 0 or 0.5.

You may not qualify if:

• Evidence of delirium, confusion
• Any neurological conditions causing cognitive decline such as Parkinson's disease, brain hemorrhage, brain tumor, normal pressure hydrocephalus
• Evidence of severe cerebrovascular pathology
• Presence of depressive symptoms that could influence cognitive function
• Presence of medical comorbidities that could result in any difficulties in study participation

Sponsors & Collaborators

• Seoul National University Bundang Hospital: lead
• Institute of Information & Communications Technology Planning & Evaluation, Korea: collaborator

Study Sites (1)

Seoul National University Bundang Hospital,

Seongnam-si, Gyeonggi-do, 13620, South Korea

Location

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Officials

• Ji Won Han, M.D., Ph.D.

  Seoul National University Bundang Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: April 24, 2019
• First Posted: April 26, 2019
• Study Start: April 17, 2019
• Primary Completion: December 31, 2019
• Study Completion: February 28, 2020
• Last Updated: March 18, 2020

Record last verified: 2020-03

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)