NCT05557032

Brief Summary

The final approach adopted in Advanced Cardiac Life Support (ACLS) guidelines as defined by the American Heart Association (AHA) and the European Resuscitation Council (ERC) is to minimize the time between chest compressions in cardiopulmonary resuscitation (CPR). Pulse and rhythm checks are recommended between chest compressions and it is stated that this period should not exceed 10 seconds. All guidelines also state that in cases of low cardiac output or low blood pressure, even if electrocardiographic (ECG) rhythms can be obtained, pulse checks may still fail and an arterial pulse may not be felt during chest compressions. This difficulty in sensing the arterial pulse causes delays in the decision of cardiac arrest in the patient. For this reason, there are cases of cardiac arrest in which the initiation of CPR is delayed or not started at all. The most common method for checking the pulse is manual palpation. However, since it is an operator-dependent method, it is affected by the experience of the healthcare personnel, the vital values of the patient, and anatomical differences. Therefore, more objective criteria are required to detect a pulse. A clinical study of the reliability of pulse checks showed that most healthcare professionals are unable to detect the presence or absence of a pulse. Another study showed that pulse alone is not sufficient to initiate CPR, and 50% of decisions to initiate CPR based on heart rate are incorrect. Therefore, more objective criteria have been sought to detect the presence of a pulse. For this purpose, evaluations were made regarding the presence of end-tidal carbon dioxide, cardiac echo, and organized rhythm.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
536

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 25, 2021

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2022

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 16, 2022

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

September 17, 2022

Completed
10 days until next milestone

First Posted

Study publicly available on registry

September 27, 2022

Completed
Last Updated

September 22, 2023

Status Verified

September 1, 2023

Enrollment Period

9 months

First QC Date

September 17, 2022

Last Update Submit

September 21, 2023

Conditions

Keywords

carotid arterypulse checkCardiopulmonary Arrest

Outcome Measures

Primary Outcomes (1)

  • Carotid artery pulse control result using manual and USG in cardiopulmonary resuscitation

    Our aim is to compare the USG and manual methods in evaluating the presence of a pulse during CPR and to determine which method gives the most appropriate time and accuracy.

    2 minute

Interventions

pulse checks during cardiopulmonary resuscitation

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients over 18 years old

You may qualify if:

  • All adult patients (over 18 years of age) with in-hospital or out-of-hospital cardiac arrest

You may not qualify if:

  • Patients with traumatic arrest
  • Conditions affecting carotid pulse palpation and/or USG application (patients with a history of carotid stenosis or dissection, patients undergoing neck surgery, patients with neck abscess hematoma)
  • Pregnant arrest patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IKCU, Atatürk Eğitim ve Araştırma Hastanesi, Acil Tıp

Izmir, 35360, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Heart Arrest

Interventions

Cardiopulmonary Resuscitation

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

ResuscitationEmergency TreatmentTherapeutics

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
1 Year
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

September 17, 2022

First Posted

September 27, 2022

Study Start

December 25, 2021

Primary Completion

September 15, 2022

Study Completion

September 16, 2022

Last Updated

September 22, 2023

Record last verified: 2023-09

Data Sharing

IPD Sharing
Will share

All data and statistical analyzes will be shared with academics and official institutions requesting the patient's names, provided that they remain confidential, after the permission of the institution.

Shared Documents
STUDY PROTOCOL, SAP, CSR

Locations