NCT05250453

Brief Summary

Patients having sudden cardiac arrest have very poor prognosis. It is devastating for patient and family. But also very expensive for nations economics when working-age people die or disable due to cardiac arrest. Recent studies have shown that high quality of cardiopulmonary resuscitation (CPR) and minimized delays increases the survival after cardiac arrest. In this objective prospective study we will use Zoll´s X Series defibrillator on every emergency medicine systems (EMS´s) unit in Pirkanmaa area, Finland, to collect information on CPR quality. Real CPR Help® will collect the information on depth, frequency and pauses during CPR. We will make an Utstein analysis on OHCA during one year period and compare the results on Utstein analysis made in the same area on 2013-2014. We will analyse the quality of CPR and compare it to the outcome from OHCA and neurological outcome 3 months after resuscitation. In addition we will analyse the CPR related injuries and compare these to the compression depth and number of persons performing CPR. In one part of the study we will evaluate the incidence of OHCA in different risk areas of Pirkanmaa and analyse the influence of time delay and location to the outcome out of hospital and neurological outcome 3 months after resuscitation. We will also analyse if the time of post-resuscitation care before getting to the hospital or stenosis in carotid artery affects the outcome from OHCA and neurological outcome 3 months after resuscitation.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
400

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2022

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

January 3, 2022

Completed
2 months until next milestone

First Posted

Study publicly available on registry

February 22, 2022

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2023

Completed
Last Updated

February 22, 2022

Status Verified

February 1, 2022

Enrollment Period

1.2 years

First QC Date

January 3, 2022

Last Update Submit

February 10, 2022

Conditions

Cardiopulmonary Resuscitation

Keywords

CPR, injuries, OHCA

Outcome Measures

Primary Outcomes (2)

  • QualityCPR

    The success rate of current guidelines (depth and frequency of chest compression, epidemiology)

    1 year

  • Neurological survival after CA

    Neurological survival after CA

    3 months after OHCA

Secondary Outcomes (4)

  • CPR related injuries

    1 year

  • Stenosis of the carotid artery

    3 months after OHCA

  • the dispatch calls concerning OHCA

    1 year

  • the quality of the postresuscitation care

    3 months after OHCA

Study Arms (3)

Cardiac arrest

All patients having sudden cardiac arrest out-of-hospital in Pirkanmaa, Finland

ResusInj

OHCA survivors having CPR related injuries or carotid stenosis analyzed by CT

ResusCPC

OHCA survivors neurological outcome

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All cardiac arrest patients in Etelä-Pohjanmaa and Pirkanmaa, Finland

You may qualify if:

  • cardiac arrest
  • \> 18 years of age

You may not qualify if:

  • \< 18 years of age
  • prisoners

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tampere University hospital

Tampere, 33521, Finland

RECRUITING

MeSH Terms

Conditions

Wounds and Injuries

Study Officials

  • Piritta Setälä, PhD

    Tampere University Hospital

    STUDY DIRECTOR

  • Sanna Hoppu, PhD

    Tampere University Hospital

    STUDY DIRECTOR

  • Jyrki Ollikainen, MD

    Tampere University Hospital

    PRINCIPAL INVESTIGATOR

  • Kati Järvelä, PhD

    Tampere University Hospital

    STUDY DIRECTOR

  • Valtteri Järvenpää, MB

    Tampere University Hospital

    PRINCIPAL INVESTIGATOR

  • Ville Jalkanen, PhD

    Tampere University Hospital

    STUDY DIRECTOR

  • Joonas Tirkkonen, PhD

    Tampere University Hospital

    STUDY DIRECTOR

  • Heini Huhtala, PhD

    Tampere University

    STUDY DIRECTOR

  • Mika Martiskainen, PhD

    Finnish Institute for Health and Welfare

    STUDY DIRECTOR

  • Riikka Nevalainen, MD

    Tampere University Hospital

    STUDY DIRECTOR

Central Study Contacts

Sanna Hoppu, PhD

CONTACT

+3583311611sanna.hoppu@pshp.fi

Paula Mäki, MD

CONTACT

+3583311611paula.maki@pshp.fi

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
3 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 3, 2022

First Posted

February 22, 2022

Study Start

January 1, 2022

Primary Completion

March 31, 2023

Study Completion

July 1, 2023

Last Updated

February 22, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will not share

Locations

FI(1)