Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong

NCT06209944 | Completed

• 1 other identifier: CCI and outcome of CPR
• Study Type: observational
• Target: 394
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to learn about the factors affecting the outcome (survival) of cardiopulmonary resuscitation in older persons in a hospital. The main questions it aims to answer are:

• Whether age would affect outcome
• Whether Charlson Comorbidity Index would affect outcome
• Whether the conditions (e.g. heart rhythm) immediately before resuscitation would affect survival. Researchers would compare the patients who deceased with the patients who survived.

Conditions

Comorbidities and Coexisting Conditions; Cardiopulmonary Resuscitation; Geriatrics

Outcome Measures

Primary Outcomes (1)

• sustained return of spontaneous circulation (ROSC), survival at 24 hours, survival at hospital discharge, and at 1 year.

  Sustained ROSC is defined as documented return of adequate circulation in the absence of ongoing chest compressions, and the duration should be of 20 minutes or above

  2017 - 2018

Interventions

Cardiopulmonary resuscitation PROCEDURE

cardiac compression, endotracheal intubation, defibrillation, and use of cardiovascular medications, to restore circulation in patients with cardiac arrest

Eligibility Criteria

• Age: 65 Years - 101 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (a regional acute hospital with total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018

You may qualify if:

• All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018
• In patients with multiple resuscitation events, only the first in-hospital CPR was included.

You may not qualify if:

• Patients with existing Do-Not-Attempt-Cardiopulmonary-Resuscitation (DNACPR) order
• Patients younger than 65 years old
• Out-of-hospital CPR in the index admission
• CPR occurred in ICU / Emergency Department / Operating Theatre / wards other than medical wards

Sponsors & Collaborators

• Jane Yidan Zhu: lead

Study Sites (1)

Haven of Hope Hospital

Hong Kong, Hong Kong, China

Location

MeSH Terms

Interventions

Cardiopulmonary Resuscitation

Intervention Hierarchy (Ancestors)

Resuscitation; Emergency Treatment; Therapeutics

Study Officials

• JANE YIDAN ZHU

  Haven of Hope Hospital, Hong Kong

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Dr Jane Yidan Zhu, Associate Consultant

Study Record Dates

• First Submitted: October 1, 2023
• First Posted: January 18, 2024
• Study Start: May 2, 2019
• Primary Completion: December 31, 2019
• Study Completion: December 31, 2019
• Last Updated: January 18, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)