Prognostic Indicators of Survival Following Cardiopulmonary Resuscitation in Patients With Cardiac Arrest

NCT03597425 | Unknown

• 1 other identifier: cardiopulmonary resuscitation
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Cardiopulmonary resuscitation (CPR) occurs approximately 200,000 times/yr in hospitals in the UnitedStates, with 18% of patients surviving to discharge. Just over half of these survivors are neurologically intact or with mild defiits at the time of discharge. Do-not-resuscitate (DNR) orders are used to withhold CPR from patients who are unlikely to benefi or for whom it is inconsistent with their treatment goals or personal preferences. It would be helpful to identify patients with a very low likelihood of survival to discharge neurologically intact or with mild defiits were they to experience cardiopulmonary arrest (CPA), so their physician can present the option of a DNR order. This information would also be useful anytime a patient raises the question of the likelihood of survival should they undergo CPA.The objective of this study was to determine key indicators for good outcome in patients with sudden cardiac arrest undergoing CPR and develop a prediction model to predict survival to hospital discharge in these patients.

Conditions

Cardiopulmonary Resuscitation

Keywords

Cardiac arrest; Cardiopulmonary resuscitation; Survival; Prediction

Outcome Measures

Primary Outcomes (1)

• indicators of survival

  The survival outcome was analyzed with logstic regression

  an average of 1 year

Interventions

Cardiopulmonary resuscitation PROCEDURE

Cardiopulmonary resuscitation (CPR) is an emergency treatment for patients with respiratory arrest and cardiac arrest in an attempt to restore the patient to spontaneous breathing and heartbeat through cardiopulmonary resuscitation

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients with cardiac arrest

You may qualify if:

• age more than 18 years,
• sudden arrest with potentially reversible causes,
• a short no fow time (time interval from presumed arrest to CPR initiation)
• even for unwitnessed arrests

You may not qualify if:

• presence of a terminal illness or malignancy, severe irreversible neurologic defcit,
• suspected or confrmed traumatic origin of arrest,
• no informed consent from the family

Sponsors & Collaborators

• First Affiliated Hospital, Sun Yat-Sen University: lead

Study Sites (1)

Genglong Liu

Shunde, Guangdong, China

RECRUITING

MeSH Terms

Conditions

Heart Arrest

Interventions

Cardiopulmonary Resuscitation

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Resuscitation; Emergency Treatment; Therapeutics

Study Officials

• Genglong Liu

  Southern Medical University, China

  STUDY CHAIR

Central Study Contacts

Genglong Liu, MD

CONTACT

+8615626405844; lglong3@mail2.sysu.edu.cn

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 13, 2018
• First Posted: July 24, 2018
• Study Start: January 1, 2017
• Primary Completion: January 1, 2020
• Study Completion: January 1, 2020
• Last Updated: July 24, 2018

Record last verified: 2018-07

Locations

CN (1)