Expression of BNDF Through Stretching and Recovery

NCT04059120 | Completed

• 1 other identifier: 090128
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The phenomena of biological adaptation and overtraining are closely related terms, that is why in sport it is possible to identify two types of overtraining. The first of these is known as short-term overtraining, which is required as a state of peripheral fatigue induced by repeated sessions of physical activity in short periods of time that are related to mechanisms of metabolic type, is considered desirable and normal, by allowing mechanisms of adaptation to be activated depending on the nature and administration of the loads, which allow reaching higher yield quotas. The second, long-term overtraining, is characterized by a series of signs and symptoms of exhaustion and persistent fatigue that take place at the level of the central nervous system and that are produced by the imbalance between demanding physical work and recovery periods.This type of condition is also known as, general syndrome of overtraining (GSO), unexplained low performance syndrome, staleness or burnout, which is propitiated by the need to achieve maximum physical performance and the performance of physical activities in a uncontrolled that cause an interruption to the processes of biological recovery that attenuate the obtaining of the physical form wished, reason why the sportsman experiences a decrease of the physical and mental performance, manifested in a clinical picture that reflects muscular inflammation, headache, elevation sudden blood pressure, loss of functional capacity, alterations of the central nervous system (CNS), metabolic, endocrine and immune systems. The stretching is commonly used as a method of physical rehabilitation. The actual information about how the GSO can reduce or prevent in the athlete are no cleared yet, that is the way the information regarding the relationship with the GSO, the stretching, the expression of BDNF and the effects can produce in the regenerative capacity in the over-trained subjects and their compensatory mechanisms during the different cycles of physical exercise, is null, making necessary the investigation of the effects that can produce in the decrease of factors that indicate GSO.

Conditions

Exercise

Keywords

Exercise; Overtraining; BDNF; Stretching

Outcome Measures

Primary Outcomes (1)

• Changes of the BDNF from basal levels to 1 and 3 month

  Measurement of serum concentration of the BDNF (pg/ml) by ELISA Method

  Baseline, 1 month to 3 month (12 weeks)

Secondary Outcomes (2)

• Changes in the testosterone/cortisol index from basal levels to 1 and 3 month

  Baseline, 1 month to 3 month (12 weeks)

• Changes of the creatine phosphokinase from basal level to 1 and 3 month

  Baseline, 1 month to 3 month (12 weeks)

Study Arms (2)

Experimental group

EXPERIMENTAL

The physical load will be organized as follows: The experimental group (EG) will perform muscle strength exercises with intensities of 45 to 90% of 1RM in combination with specific stretching exercises, and aerobic resistance with efforts of 60 to 90% of the theoretical maximum heart rate, which will be controlled with a Polar brand heart rate monitor model FT7.

Other: Experimental group whit specific stretching

Control group

ACTIVE COMPARATOR

The physical load will be organized as follows: The control group (CG) will perform muscle strength exercises with intensities of 45 to 90% of 1RM in combination with single or general stretching exercises, and aerobic resistance with efforts of 60 to 90% of the theoretical maximum heart rate, which will be controlled with a Polar brand heart rate monitor model FT7.

Other: Control group whit out specific stretching

Interventions

Experimental group whit specific stretching OTHER

The intervention involves a reality of physical, physical, different exercise, similar to the realist of high-performance athletes. However, this is the physical load, which is reduced with specific exercises of stretching and with it the factors that determine the syndrome of overtraining

Experimental group

Control group whit out specific stretching OTHER

The intervention involves a reality of physical, physical, different exercise, similar to the realist of high-performance athletes. However, this is the physical load, which is reduced less than specific exercises of stretching and with it the factors that determine the syndrome of overtraining

Control group

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Be a student of the degree in physical education and sports at the University of Colima.
• Men with ages from 18 to 25 years.
• Lead a moderate sedentary or active recreational lifestyle
• Sign the act of voluntary participation in the study, with the precise knowledge of the qualifications and the procedures applied.
• Having completed the Tecumseh test, passing the test and knowing the level of physical fitness
• Have been diagnosed as healthy after being submitted to the clinical assessment.

You may not qualify if:

• Presenting metabolic alterations such as type I or II diabetes
• Having chronic respiratory diseases such as pulmonary, chronic obstructive disease, asthma, emphysema or cancer.
• Having high blood pressure or arrhythmia.
• Be under a physical training of muscular strength or aerobic resistance with high-performance direction.
• Be under some drug treatment or drug use.
• Elimination criteria
• All subjects who wish to leave the study voluntarily
• Those subjects who present ostiomyoarticular and skeletal injuries caused by the physical exercise performed. A medical specialist in sports medicine, a person at work, a medical care channel.
• Subjects who present symptoms of wear or corrosion during the training received. Same that will be directed to make a break, in addition to attended and monitored by a sports doctor. From the need for more attention, they will be channeled to the familiar doctor.
• Those who do not comply with 70% attendance to the physical training program

Sponsors & Collaborators

• Universidad de Colima: lead

Study Sites (1)

Universidad de Colima

Colima, 28040, Mexico

Location

Related Publications (12)

• Tanaka H, Monahan KD, Seals DR. Age-predicted maximal heart rate revisited. J Am Coll Cardiol. 2001 Jan;37(1):153-6. doi: 10.1016/s0735-1097(00)01054-8.

  PMID: 11153730 BACKGROUND

• Wilmore, JH & Costill DL Physiology of effort and sport. 2007. Paidotribo. Spain

  BACKGROUND

• Meeusen R, Duclos M, Foster C, Fry A, Gleeson M, Nieman D, Raglin J, Rietjens G, Steinacker J, Urhausen A; European College of Sport Science; American College of Sports Medicine. Prevention, diagnosis, and treatment of the overtraining syndrome: joint consensus statement of the European College of Sport Science and the American College of Sports Medicine. Med Sci Sports Exerc. 2013 Jan;45(1):186-205. doi: 10.1249/MSS.0b013e318279a10a.

  PMID: 23247672 BACKGROUND

• Wyatt, FB, Donaldson, A, & Brown, E. The overtraining syndrome: A meta-analytic review. Journal of exercise physiology. 16 (2), 12-23, 2013

  BACKGROUND

• Bergado, J, Lorigados, L. Alberti, E. & Almaguer, W. Neurotrophic factor derived from the brain in brain tissue of healthy rats. Journal CENIC Biological Sciences, 2 (40), 135 - 139, 2009

  BACKGROUND

• González, R, Miller, R, Martínez, R, Andrade, A & Márquez, S. Adaptation in sport and its relation to overtraining. Notebooks of sports psychology. 6 (1), 81-98, 2006.

  BACKGROUND

• Huesca, JM. Analysis of the general index of flexibility. Sports medicine 71 (2): 65-69, 2004

  BACKGROUND

• Mackenzie, B. 101 Performance evaluation tests. Electric Word plc. 2005

  BACKGROUND

• Budgett R. Overtraining syndrome. Br J Sports Med. 1990 Dec;24(4):231-6. doi: 10.1136/bjsm.24.4.231.

  PMID: 2097018 RESULT

• Sesboue B, Guincestre JY. Muscular fatigue. Ann Readapt Med Phys. 2006 Jul;49(6):257-64, 348-54. doi: 10.1016/j.annrmp.2006.04.021. Epub 2006 Apr 27. English, French.

  PMID: 16757054 RESULT

• Kreher JB, Schwartz JB. Overtraining syndrome: a practical guide. Sports Health. 2012 Mar;4(2):128-38. doi: 10.1177/1941738111434406.

  PMID: 23016079 RESULT

• Jackson AS, Blair SN, Mahar MT, Wier LT, Ross RM, Stuteville JE. Prediction of functional aerobic capacity without exercise testing. Med Sci Sports Exerc. 1990 Dec;22(6):863-70. doi: 10.1249/00005768-199012000-00021.

  PMID: 2287267 RESULT

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

• Del Río Va José Encarnación, PhD

  Universidad de Colima

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: The blindness will be on the part of the subjects do not recognize the type of stretching training that is being done
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Msc

Model Details: The model of the physical training program to follow is. The subjects will perform a physical exercise for 12 weeks divided into three blocks of 4 periods, organized in 3 weeks of training, plus 1 rest, which simulate physical loads similar to the periods of competition used in high-performance sports. The evaluations will be made prior to the training (basal measurement) and at the end of each of the blocks during the rest period. The physical load will be organized as follows: The control group (CG) will perform muscle strength exercises with intensities of 45 to 90% of 1RM, as well as aerobic resistance with efforts of 60 to 90% of the theoretical maximum heart rate, which will be controlled with a Polar brand heart rate monitor model FT7. Like the CG, the experimental group (EG) will perform the same physical load of muscular strength and aerobic resistance in combination with specific stretching exercises

Study Record Dates

• First Submitted: March 5, 2019
• First Posted: August 16, 2019
• Study Start: March 30, 2018
• Primary Completion: June 23, 2020
• Study Completion: August 17, 2020
• Last Updated: March 4, 2021

Record last verified: 2021-03

Data Sharing

• IPD Sharing: Will not share

Locations

ME (1)