NCT03696147

Brief Summary

The aim of the study is to identify the role of diffusion weighted MRI in the assessment of the clinical significance and outcomes of asymmetric breast densities identified on mammograms, and to identify the inconclusive mammographic findings most frequently associated with occult breast carcinoma.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Dec 2018

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 3, 2018

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 4, 2018

Completed
2 months until next milestone

Study Start

First participant enrolled

December 1, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2019

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2019

Completed
Last Updated

October 30, 2018

Status Verified

October 1, 2018

Enrollment Period

7 months

First QC Date

October 3, 2018

Last Update Submit

October 27, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Comparison of diffusion MRI finding with the pathology of the specimens

    Analysis of diffusion weighted images and ADC values to defferntiate different pathologies causing asymmetric densities in routine screening or diagnostic mammography

    Baseline

Interventions

Diffusion weighted sequence of MRI

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

sample size was calculated using EpiInfo7statcalc. Prog. With the following input population size: 120 expected frequency: 6% confidence limits: 5% design effect: 1.0 clusters: 1 The sample size was 50 cases at 95%confidence level.

You may qualify if:

  • All patients presented with asymmetric breast densities, seen on screening or diagnostic mammograms.

You may not qualify if:

  • Patients with cardiac pacemakers.
  • Patients with brain aneurysm clips.
  • Patients with cochlear implants.
  • Patients with vascular stents.
  • Claustrophobic.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Magnetic Resonance Imaging

Intervention Hierarchy (Ancestors)

TomographyDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosis

Central Study Contacts

Shimaa Ali Saad, Master

CONTACT

Eman Abo Elhamd Ahmad, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant lecturer

Study Record Dates

First Submitted

October 3, 2018

First Posted

October 4, 2018

Study Start

December 1, 2018

Primary Completion

July 1, 2019

Study Completion

October 1, 2019

Last Updated

October 30, 2018

Record last verified: 2018-10