Success Metrics

Clinical Success Rate
80.7%

Based on 218 completed trials

Completion Rate
81%(218/270)
Active Trials
564(56%)
Results Posted
55%(119 trials)
Terminated
52(5%)

Phase Distribution

Ph early_phase_1
31
3%
Ph phase_2
313
31%
Ph not_applicable
189
19%
Ph phase_1
199
20%
Ph phase_4
11
1%
Ph phase_3
90
9%

Phase Distribution

230

Early Stage

313

Mid Stage

101

Late Stage

Phase Distribution833 total trials
Early Phase 1First-in-human
31(3.7%)
Phase 1Safety & dosage
199(23.9%)
Phase 2Efficacy & side effects
313(37.6%)
Phase 3Large-scale testing
90(10.8%)
Phase 4Post-market surveillance
11(1.3%)
N/ANon-phased studies
189(22.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.6%

218 of 318 finished

Non-Completion Rate

31.4%

100 ended early

Currently Active

564

trials recruiting

Total Trials

1,009

all time

Status Distribution
Active(611)
Completed(218)
Terminated(100)
Other(80)

Detailed Status

Recruiting358
Completed218
Active, not recruiting206
unknown63
Terminated52
Withdrawn48

Development Timeline

Analytics

Development Status

Total Trials
1009
Active
564
Success Rate
80.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 131 (3.7%)
Phase 1199 (23.9%)
Phase 2313 (37.6%)
Phase 390 (10.8%)
Phase 411 (1.3%)
N/A189 (22.7%)

Trials by Status

unknown636%
enrolling_by_invitation71%
withdrawn485%
recruiting35835%
terminated525%
active_not_recruiting20620%
completed21822%
not_yet_recruiting404%
suspended172%

Recent Activity

Clinical Trials (1,009)

Showing 20 of 1,009 trialsScroll for more
NCT07544992Phase 1

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

Recruiting
NCT05095376Phase 3

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Active Not Recruiting
NCT06589804Phase 3

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Recruiting
NCT04402788Phase 2

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Recruiting
NCT06307548Phase 1

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer

Recruiting
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT04847453Phase 1

Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis

Active Not Recruiting
NCT05111574Phase 2

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT05773274Phase 2

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Recruiting
NCT04166409Phase 3

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Recruiting
NCT05136196Phase 2

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Recruiting
NCT05642572Phase 2

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

Recruiting
NCT06022939Phase 3

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

Recruiting
NCT04657042

4D-MRI for Precision Medicine

Recruiting
NCT05904080Phase 2

Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer

Recruiting
NCT04181060Phase 3

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Recruiting
NCT06116682Phase 2

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

Recruiting
NCT05987241Phase 2

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
1,009