Protocol of Multi-domain Attention Training

NCT03379519 | Completed DMC

• 1 other identifier: N201602069
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study sought to investigate the changes in attention in older adults with mild cognitive impairment after Multi-domain Attention Training .

Conditions

Mild Cognitive Impairment

Outcome Measures

Primary Outcomes (1)

• Change in attention as measured by the Digit Span Task (DS).

  The primary outcome indicators is executive attention assessed by the Digit Span Task (DS).

  Change from baseline in executive attention at Immediate post-test, 3 months, 6 months after intervention.

Secondary Outcomes (1)

• Change in attention as measured by the Trail Making Test (TMT).

  Change from baseline in spatial orienting attention at Immediate post-test, 3 months, 6 months after intervention.

Study Arms (2)

Multi-domain Attention Training (MAT)

EXPERIMENTAL

Training sessions of the MAT group is 45 minutes/day, 3 sessions/week, for 12 weeks (36 sessions).

Behavioral: Multi-domain Attention Training (MAT)

Passive information activities (PIA)

ACTIVE COMPARATOR

The training sessions of PIA is the same as MAT group (45 min/day, 3 days/week, for 12 weeks, for a total of 36 sessions).

Behavioral: Passive information activities (PIA)

Interventions

Multi-domain Attention Training (MAT) BEHAVIORAL

The training content emphasis three concept of attention include: intensity of attention, executive attention, and spatial orienting attention.

Also known as: Attention training

Multi-domain Attention Training (MAT)

Passive information activities (PIA) BEHAVIORAL

The active control group (Passive information activities) training content included reading online e-books and playing online games.

Also known as: Active control group

Passive information activities (PIA)

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Participants must endorse at least two items from a list of frequent subjective memory complaints by patient and/or an informant
• Objective memory impairment on neuropsychological tests of memory 1.5 SD or more below age/education norms
• Clinical neurologic examination by the Mini-Mental State Examination (MMSE) score of 24 or higher
• No impairment in personal activities of daily living (P-ADL) as determined by clinical interview with participant and family

You may not qualify if:

• The clinical diagnosis of dementia was based on the DSM-IV-TR
• Active in another cognitive or memory-related training in the past year
• Comorbid medical conditions that would predispose them to imminent functional decline or cognitive impairment
• A diagnosis of major neurological or psychiatric illness history and/or behavioral problems that would sufficiently impair performance to make participation impossible
• Severe losses in vision, hearing, or communicative ability

Sponsors & Collaborators

• Ministry of Science and Technology, Taiwan: lead

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ph.D. candidate

Study Record Dates

• First Submitted: December 10, 2017
• First Posted: December 20, 2017
• Study Start: August 1, 2016
• Primary Completion: May 31, 2019
• Study Completion: December 31, 2019
• Last Updated: February 20, 2020

Record last verified: 2020-02

Data Sharing

• IPD Sharing: Will not share