NCT03155815

Brief Summary

The purpose of this study is to develop and validate the Dementia Population Risk Tool (DemPoRT) algorithm to predict dementia incidence in the population setting.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75,460

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2000

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2000

Completed
13.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2014

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

May 11, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 16, 2017

Completed
2.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

February 17, 2020

Status Verified

February 1, 2020

Enrollment Period

13.5 years

First QC Date

May 11, 2017

Last Update Submit

February 13, 2020

Conditions

Dementia

Outcome Measures

Primary Outcomes (1)

  • Dementia capture in administrative data

    Identification of incident dementia in administrative data using a validated case ascertainment definition, supplemented by dementia codes captured on home care and long-term care assessments

    Up to 13 years

Study Arms (2)

Derivation Cohort

Eligible respondents to the combined 2001, 2003, 2005 and 2007 Canadian Community Health Surveys, conducted by Statistics Canada.

Validation Cohort

Eligible respondents to the 2008/2009 Canadian Community Health Survey.

Eligibility Criteria

Age55 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The derivation cohort will be eligible respondents to the combined 2001, 2003, 2005 and 2007 Canadian Community Health Surveys, conducted by Statistics Canada. The validation cohort will consist of respondents to the 2008/2009 survey.

You may qualify if:

  • Respondents to the Canadian Community Health Surveys

You may not qualify if:

  • Less than 55 years of age at survey administration
  • Prior history of dementia
  • Not eligible for Ontario's universal health insurance program

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Fisher S, Hsu A, Mojaverian N, Taljaard M, Huyer G, Manuel DG, Tanuseputro P. Dementia Population Risk Tool (DemPoRT): study protocol for a predictive algorithm assessing dementia risk in the community. BMJ Open. 2017 Oct 24;7(10):e018018. doi: 10.1136/bmjopen-2017-018018.

    PMID: 29070641BACKGROUND

MeSH Terms

Conditions

Dementia

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental Disorders

Study Officials

  • Peter Tanuseputro

    Ottawa Hospital Research Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 11, 2017

First Posted

May 16, 2017

Study Start

September 1, 2000

Primary Completion

March 1, 2014

Study Completion

December 1, 2019

Last Updated

February 17, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share