Impact of Hospital Admission on Patients With Dementia

NCT02483065 | Unknown

• 1 other identifier: 2012111139
• Study Type: observational
• Target: 413
• Locations: 0 countries
• Sites: N/A

Brief Summary

People with dementia have complex medical, social, and psychological needs and can be exacerbated by physical illness and the complex relationships between health care systems, patients and their families or caregivers. They are a vulnerable and fragile population that differs significantly from the population without dementia. Therefore, the investigators propose the following objectives: 1. To describe the evolution of dementia patients admitted during the study period in two hospitals in the Basque Health Service-Osakidetza and complications associated with such admissions. 2. To compare with a control group (matched by type of pathology, age and sex and adjusting for other clinical variables (severity of dementia ...) the patient's condition before and after admission, in terms of quality of life, dependency, instrumental activities of daily living and severity of dementia. 3. To compare the length of stay, complications, mortality rate, the degree of dependency and quality of life of patients with dementia compared to those without dementia, matched by groups of pathologies, gender and age.

Conditions

Dementia

Keywords

dementia; hospital admission; mortality; health-related quality of life; activities of daily living

Outcome Measures

Primary Outcomes (1)

• Mortality during hospitalization and at follow-up

  In-hospital mortality, and at follow-up: information on survival status of the patients was collected during hospitalization and assessed 3 months after discharge by telephone interview to patients or caregivers.

  Up to 3 months

Secondary Outcomes (11)

• The Alzheimer's Disease Test (AD8)

  Up to 3 months

• Assessment of Performance in Basic Activities of Daily Living: Barthel Index

  Up to 3 months

• Instrumental Activities of Daily Living (IADL)

  Up to 3 months

• EuroQoL 5-domain for Health-related quality of life (EQ-5D) (EuroQoL Group, 1990).

  Up to 3 months

• The Quality of Life in Alzheimer's disease (QOL-AD)

  Up to 3 months

Study Arms (2)

inpatients with dementia

Other: mortality at discharge and 3-months after the admission in patients with and without dementia

inpatients without dementia

Other: mortality at discharge and 3-months after the admission in patients with and without dementia

Interventions

mortality at discharge and 3-months after the admission in patients with and without dementia OTHER

Patients diagnosed of dementia who ingresed the hospital were informed of the goals of the study and invited to voluntarily participate. In order to take part in the study, patients were required to provide informed consent. All participants were first screened with the Alzheimer's Disease Test. A diagnosis of dementia was generated by an independent clinician experienced in old age psychiatry using a structured clinical assessment based on operationalized DSM-IV criteria. Clinical data were gathered from hospital notes. Information on sociodemographic data, premorbid basic and instrumental activities of daily living, quality of life and burden of the caregiver was gathered from carers and review of hospital notes. In both cohorts, participants were telephoned 3 months after hospital admission to respond the follow-up questionnaires. Patients who decided not to answer them were considered lost to follow-up. All information was kept confidential.

inpatients with dementia; inpatients without dementia

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

For this prospective matched cohort study, the investigators recruited two groups of adults aged 75 years and older with an unplanned medical admission to any medical speciality between January 2012 and December 2014 in the Galdakao-Usansolo Hospital in the Basque Country (northern Spain), a 400-bed general teaching hospital serving a population of 300,000. It is one of the networks of public hospitals of the Basque Health Service, which provides free unrestricted care to nearly 100% of the population. One group (patients with dementia cohort) was drawn from patients with dementia, and a second group (patients without dementia cohort) of patients without dementia.

You may not qualify if:

• Patients with dementia (or caregivers) were excluded if they did not provide inform consent.

Sponsors & Collaborators

• Hospital Galdakao-Usansolo: lead
• Department of Health, Basque Country, Spain: collaborator

MeSH Terms

Conditions

Dementia

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders

Study Officials

• Inmaculada Moro, MSc

  Hospital Galdakao-Usansolo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: June 18, 2015
• First Posted: June 26, 2015
• Study Start: January 1, 2012
• Primary Completion: January 1, 2015
• Last Updated: June 26, 2015

Record last verified: 2015-06