Mortality Risk Prediction Tool in Hospitalized Dementia Patients
The Development and Validation of a Clinical Prediction Tool to Estimate 1-year Mortality Among Hospitalized Patients With Dementia
1 other identifier
observational
298,576
0 countries
N/A
Brief Summary
The objective of this study is to develop and validate a clinical prediction tool to estimate 1-year mortality among hospitalized patients with dementia.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Apr 2009
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
March 31, 2020
CompletedFirst Submitted
Initial submission to the registry
May 7, 2022
CompletedFirst Posted
Study publicly available on registry
May 12, 2022
CompletedMay 12, 2022
May 1, 2022
11 years
May 7, 2022
May 7, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Mortality
Derived from population-based administrative database
Within 1 year of admission
Study Arms (2)
Derivation cohort
The derivation cohort will comprise about 235,000 patients with dementia, who were admitted to a hospital in Ontario from April 1st, 2009 to December 31st, 2017.
Validation cohort
The validation cohort will comprise about 63,000 dementia patients, who were admitted to a hospital in Ontario from January 1st, 2018 to March 31st, 2019.
Eligibility Criteria
The derivation cohort will comprise about 235,000 patients with dementia, who were admitted to a hospital in Ontario from April 1st, 2009 to December 31st, 2017. The validation cohort will comprise about 63,000 dementia patients, who were admitted to a hospital in Ontario from January 1st, 2018 to March 31st, 2019.
You may qualify if:
- Diagnosis of dementia using a validated algorithm to identify cases based on a combination of hospital codes, physician claims, and prescribed medications that are specific to dementia
- Hospitalization at least once from March 31st, 2009, to April 1st, 2019
You may not qualify if:
- Age \<65 years at the time of index admission
- Ineligibility for universal health insurance at the time of admission
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Torontolead
- Canadian Institutes of Health Research (CIHR)collaborator
- ICEScollaborator
Related Publications (1)
Bonares M, Fisher S, Quinn K, Wentlandt K, Tanuseputro P. Study protocol for the development and validation of a clinical prediction tool to estimate the risk of 1-year mortality among hospitalized patients with dementia. Diagn Progn Res. 2024 Mar 19;8(1):5. doi: 10.1186/s41512-024-00168-2.
PMID: 38500236DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer
Study Record Dates
First Submitted
May 7, 2022
First Posted
May 12, 2022
Study Start
April 1, 2009
Primary Completion
March 31, 2020
Study Completion
March 31, 2020
Last Updated
May 12, 2022
Record last verified: 2022-05
Data Sharing
- IPD Sharing
- Will not share