NCT03080636

Brief Summary

The present study compared the acute effects of Sex and exercise mode on subsequent blood pressure (BP) and heart rate variability (HRV) responses during daily work in healthy adults. All subjects did 3 sessions: aerobic exercise on a treadmill, resistance exercise at the gym and a seated control session.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2014

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 24, 2014

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 20, 2015

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

March 7, 2017

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 15, 2017

Completed
Last Updated

March 15, 2017

Status Verified

March 1, 2017

Enrollment Period

12 months

First QC Date

March 7, 2017

Last Update Submit

March 9, 2017

Conditions

Keywords

Post-exercise hypotensionAerobic ExerciseResistance ExerciseAutonomic StressHeart Rate VariabilitySex difference

Outcome Measures

Primary Outcomes (2)

  • Resting blood pressure

    During all sessions, systolic (SBP) and diastolic blood pressure (DBP) were triplicate measured by an automatic blood pressure analyzer after rest in seated position.

    Change from baseline Systolic and Diastolic Blood Pressure to 15, 30, 45, 60, 210, 360 and 540 minutes after exercise/control session

  • Heart Rate Variability

    The HR was recorded by a heart rate monitor (sampling frequency = 1000Hz) in a beat-by-beat basis. HR was registered in a seat position during 15 minutes for each measure.

    Change from baseline Heart Rate Variability components to 15, 30, 45 and 60 minutes after exercise/control session

Study Arms (2)

Men

EXPERIMENTAL

11 men randomly underwent three experimental sessions in early morning prior to their work routine.

Other: Aerobic exerciseOther: Resistance exerciseOther: Control session

Women

EXPERIMENTAL

9 women randomly underwent three experimental sessions in early morning prior to their work routine.

Other: Aerobic exerciseOther: Resistance exerciseOther: Control session

Interventions

30 minutes of treadmill exercise at 60-70% of heart rate reserve

MenWomen

30 minutes of circuit resistance session at 40% of 1 maximun repetition test

MenWomen

30 minutes seated resting

MenWomen

Eligibility Criteria

Age28 Years - 54 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Able to practice aerobic and resistance exercise at moderate intensity;
  • Men and women;
  • Normotensive, pre-hypertensive or hypertensive stage 1.

You may not qualify if:

  • Renal pathologies;
  • Using beta blockers;
  • History of stroke or acute myocardial infarction;
  • Smokers.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Guilherme Morais Puga

Uberlândia, Minas Gerais, 38400-678, Brazil

Location

Related Publications (5)

  • Gomes Anunciacao P, Doederlein Polito M. A review on post-exercise hypotension in hypertensive individuals. Arq Bras Cardiol. 2011 May;96(5):e100-109. Epub 2011 Mar 4. English, Portuguese, Spanish.

    PMID: 21359479BACKGROUND
  • Halliwill JR, Buck TM, Lacewell AN, Romero SA. Postexercise hypotension and sustained postexercise vasodilatation: what happens after we exercise? Exp Physiol. 2013 Jan;98(1):7-18. doi: 10.1113/expphysiol.2011.058065. Epub 2012 Aug 7.

    PMID: 22872658BACKGROUND
  • Queiroz AC, Rezk CC, Teixeira L, Tinucci T, Mion D, Forjaz CL. Gender influence on post-resistance exercise hypotension and hemodynamics. Int J Sports Med. 2013 Nov;34(11):939-44. doi: 10.1055/s-0033-1337948. Epub 2013 Apr 19.

    PMID: 23606339BACKGROUND
  • Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J. 1996 Mar;17(3):354-81. No abstract available.

    PMID: 8737210BACKGROUND
  • Cote AT, Bredin SS, Phillips AA, Koehle MS, Warburton DE. Greater autonomic modulation during post-exercise hypotension following high-intensity interval exercise in endurance-trained men and women. Eur J Appl Physiol. 2015 Jan;115(1):81-9. doi: 10.1007/s00421-014-2996-5. Epub 2014 Sep 11.

    PMID: 25208772BACKGROUND

MeSH Terms

Conditions

Motor ActivityPost-Exercise Hypotension

Interventions

ExerciseResistance Training

Condition Hierarchy (Ancestors)

BehaviorOrthostatic IntolerancePrimary DysautonomiasAutonomic Nervous System DiseasesNervous System DiseasesHypotensionVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaExercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, Human

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Model Details: 20 healthy adults, public servants (9W and 11M), randomly underwent three experimental sessions in early morning prior to their work routine: a circuit resistance session at 40% of 1RM, a treadmill exercise session at 60-70% of heart rate reserve and a resting control session.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 7, 2017

First Posted

March 15, 2017

Study Start

January 1, 2014

Primary Completion

December 24, 2014

Study Completion

February 20, 2015

Last Updated

March 15, 2017

Record last verified: 2017-03

Locations