NCT00761163

Brief Summary

The purpose of this study is to identify the body's response to aerobic vs. resistance exercise. Throughout this study, we will examine food intake, appetite, and physical and mental well-being before, during, and after aerobic and resistance exercise.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2007

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2007

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

September 25, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 29, 2008

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2008

Completed
Last Updated

January 17, 2013

Status Verified

January 1, 2013

Enrollment Period

1.8 years

First QC Date

September 25, 2008

Last Update Submit

January 16, 2013

Conditions

Keywords

The purpose of this study is to identify the body's response to aerobic vs. resistance exercise

Outcome Measures

Primary Outcomes (2)

  • Physical well being via electrocardiogram and body composition

    5-6 weeks

  • Mental well being via questionnaires

    5-6 weeks

Study Arms (3)

1

EXPERIMENTAL
Other: Resistance Exercise

2

EXPERIMENTAL
Other: Aerobic Exercise

3

EXPERIMENTAL
Other: Control (Non-exercise)

Interventions

The subjects will complete 2 resistive exercise sessions on non-consecutive days that will be supervised by our laboratory staff. The following exercises will be performed using the Keiser Sports Health equipment in Ismail Health, Exercise, and Nutrition Center: seated row, double leg press, seated leg curl, chest press, and leg extension. The subjects will individually perform 3 sets of 8-10 repetitions at an exercise intensity of 70% of pre-determined maximal strength for these exercises. Each repetition will be performed in a slow (six to eight seconds) uniform fashion, giving equal time to the concentric (muscle shortening) and eccentric (muscle lengthening) portions. One minute of rest will be allowed between sets. The last repetition of the third set of each exercise will be done to voluntary fatigue or the performance of 12 repetitions.

1

The subjects will complete 2 aerobic exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. The subjects will perform 45 minutes of aerobic exercise on a stationary bike at an exercise intensity of 70% of their heart-rate reserve.

2

The subjects will also complete 2 non-exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. These sessions will consist of incorporating diversionary tasks throughout a 45 minute period consisting of a variety of motor and psychological tasks (tests of hand steadiness, alertness, optical illusions, mental acuity, etc.)

3

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body mass index between 18-29 kg/m2
  • Weight stable (\< 4.5 kg weight change within last 6 months)
  • Non-smoking
  • Constant habitual activity patterns within last 3 months
  • Non-diabetic
  • Resistive exercise training (≥ 2 times a week) based on reported physical activity levels (questionnaire)
  • Aerobic exercise training (≥ 2 times a week, 30-min sessions) based on reported physical activity levels (questionnaire)
  • Confirmation of acceptability of eating the study test foods (macaroni casserole)
  • Approved to participate in this study by our study physician and principle investigator
  • The older subjects must also meet the following eligibility criteria:
  • Age range: 65 years and older
  • Body fat (women: \<38%; men: \<28%)
  • Normal resting EKG as assessed by a Cardiologist
  • The younger subjects must also meet the following eligibility criteria:
  • Age range: 18-29 years
  • +1 more criteria

You may not qualify if:

  • Body mass index: outside of the 18-29 kg/m2 range
  • Gained or lost \> 4.5 kg within the last 6 months
  • Smoker (currently or within the last year)
  • Intermittently been involved in a diet and/or exercise program within the last 3 months
  • Clinically diagnosed as diabetic
  • Did not perform resistive exercise training (currently or within the last 3 months) based on reported physical activity levels (questionnaire)
  • Did not perform adequate aerobic exercise (currently or within the last 3 months) based on physical activity levels (questionnaire)
  • Study food is found to be unacceptable for consumption by the subject
  • Unapproved to participate in this study by our study physician and principle investigator
  • The older subjects:
  • Age range: \<65 yrs
  • Body fat (women: \>38%; men: \>28%)
  • The younger subjects:
  • Age range: outside the \>29 yrs or \<18 yrs
  • Body fat (women: \>28%; men: \>18%)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Purdue University

West Lafayette, Indiana, 47907, United States

Location

Related Publications (1)

  • Laan DJ, Leidy HJ, Lim E, Campbell WW. Effects and reproducibility of aerobic and resistance exercise on appetite and energy intake in young, physically active adults. Appl Physiol Nutr Metab. 2010 Dec;35(6):842-7. doi: 10.1139/H10-072.

MeSH Terms

Conditions

Motor Activity

Interventions

Resistance TrainingExercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Wayne Campbell, Ph. D.

Study Record Dates

First Submitted

September 25, 2008

First Posted

September 29, 2008

Study Start

February 1, 2007

Primary Completion

November 1, 2008

Study Completion

November 1, 2008

Last Updated

January 17, 2013

Record last verified: 2013-01

Locations