Effects OF Acute Aerobic Exercise On Higher Cerebral Functions

NCT05861726 | Unknown DMC

• 1 other identifier: 148/DME/KMC
• Study Type: interventional
• Target: 38
• Locations: 0 countries
• Sites: N/A

Brief Summary

We are comparing higher cerebral functions including cognitive flexibility, inhibitory control and working memory in healthy young adults between a group of acute aerobic exercise and a control group.

Conditions

Exercise

Outcome Measures

Primary Outcomes (5)

• Change in performance of Stroop Test before & after an acute session of aerobic exercise

  Stroop test will be used to assess cognitive flexibility aspect of "executive brain functions". The reaction time in milliseconds to identify the congruent and incongruent words in the stroop test will be measured.

  Change in the reaction time of stroop test 5 minutes before and 3 minutes after aerobic exercise will be recorded

• Change in performance of "Stop Signal Task Test" before & after an acute session of aerobic exercise.

  "Stop signal task" test will be used to assess the inhibitory control aspect of "executive brain functions". The response time in milliseconds will be measured in the test.

  Change in the response time 5 minutes before and 3 minutes after aerobic exercise will be recorded

• Change in performance of "Stop Signal Task Test" before & after an acute session of aerobic exercise.

  "Stop signal task" test will be used to assess the inhibitory control aspect of "executive brain functions". Status of the response(1=correct, 2=wrong, 3=timeout) will be measured in the test.

  Change in status of the response 5 minutes before and 3 minutes after aerobic exercise will be recorded

• Change in performance of "N-Back task/2-Back task " before & after an acute session of aerobic exercise.

  "N-Back task/2-Back task" test will be used to assess the working memory aspect of "executive brain functions". The reaction time taken in milliseconds to correctly match target letters in the test will be measured.

  Change in reaction time 5 minutes before and 3 minutes after an acute session of aerobic exercise will be recorded

• Change in performance of "N-Back task/2-Back task " before & after an acute session of aerobic exercise.

  "N-Back task/2-Back task" test will be used to assess the working memory aspect of "executive brain functions". The number of false alarms on the test will be measured.

  Change in the number of false alarms 5 minutes before and 3 minutes after an acute session of aerobic exercise will be recorded

Study Arms (2)

Exercising Group

ACTIVE COMPARATOR

The exercising group shall have pre-intervention assessment of executive brain functions vide Stroop test, Trail making test \& N-Back task/2-Back by using online psytoolkit followed by intervention. The intervention for the group being acute aerobic exercise, which will comprise of 30 minutes of treadmill walking at 60-65% of Heart Rate max with continuous recording of heart rate and ECG via Biopac MP36 Student Lab system. This will be followed by post-intervention assessment of executive brain functions vide Stroop test, Trail making test \& N-Back task/2-Back by using online psytoolkit.

Behavioral: Aerobic exercise

Control Group

PLACEBO COMPARATOR

The control group will also have pre-intervention assessment of executive brain functions vide Stroop test, Trail making test \& N-Back task/2-Back by using online psytoolkit. The control group will undergo NO EXERCISE intervention. They will sit idly in laboratory for 30 minutes with continuous recording of heart rate and ECG via Biopac system. The executive brain functions of the control group will be re-assessed vide Stroop test, Trail making test \& N-Back task/2-Back by using online psytoolkit.

Other: None (control group)

Interventions

Aerobic exercise BEHAVIORAL

a moderate kind of physical activity with a heart rate between 65 \& 70% maximum heart rate

Exercising Group

None (control group) OTHER

None (the control group)

Control Group

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy young adults

You may not qualify if:

• smokers
• cardiorespiratory disorders
• psychiatric disorders

Sponsors & Collaborators

• Khyber Medical College, Peshawar: lead

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise; Control Groups

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 14, 2023
• First Posted: May 17, 2023
• Study Start: June 1, 2023
• Primary Completion: August 31, 2023
• Study Completion: September 30, 2023
• Last Updated: May 17, 2023

Record last verified: 2023-04

Data Sharing

• IPD Sharing: Will not share