Future Mental Projections in Schizophrenia

NCT03040505 | Terminated

• 1 other identifier: 6527
• Study Type: observational
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to investigate temporal organization of future thinking in patients with schizophrenia. Patients and control participants will be asked to envision and briefly describe ten personal future events using a cue-words list. Then they will be asked to describe everything that came to their minds (i.e. to think aloud) while they attempted to determine when an event will likely occur. The investigators will compare the proportion of several predefined strategies mentioned by the two groups of participants to locate future events in time. The investigators predict that patients will envision less personal future events and will rely to a lesser extent on strategies to locate events in time, than control participants.

Conditions

Schizophrenia

Outcome Measures

Primary Outcomes (1)

• Number of time location strategies

  1 months

Study Arms (2)

Patients with schizophrenia

Patients with schizophrenia or schizoaffective disorder according to DSM-V criteria

Other: questionnary

Control participants

\- Control participants without psychiatric nor neurological history

Other: questionnary

Interventions

questionnary OTHER

Participant's verbalization will be audio recorded and then transcribed by investigators. The investigators will use predefined categories to score the strategies mentioned by participants during the think aloud task.

Control participants; Patients with schizophrenia

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

patients with Schizophrenia

You may qualify if:

• for patients only
• male or female
• age limits : 18-55 years old
• under the protection of health insurance
• who have signed up the consent form
• schizophrenia or schizo-affective disorder according to the DSM-5 criteria (APA, 2013).
• clinically stable for at least 2 months
• patients under guardianship or curatorship need agreement of their legal representative
• informed of the results of prior medical examination for controls only
• male or female
• age limits : 18-55 years old
• under the protection of health insurance
• who have sign up the consent form
• recruited from the general population and matched on gender, age years of schooling
• no psychiatric history (DSM-5)

You may not qualify if:

• for both patients and controls
• current severe or unstable somatic illness
• neurological history (brain injury \> 15 minutes loss of consciousness , epilepsia, brain surgery…)
• current substance use disorder (DSM-5)
• current major depressive disorder (CDSS,BDI, HDRS)
• mental retardation (IQ \< 70, WAIS-4, f-NART)
• history of general anesthesia 3 months prior to the experiment
• pregnancy declared by the subject
• breast feeding
• current legal control
• in emergency situation
• for controls only
• under guardianship or curatorship

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de psychiatrie 1

Strasbourg, 67000, France

Location

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 27, 2017
• First Posted: February 2, 2017
• Study Start: April 5, 2017
• Primary Completion: October 20, 2019
• Study Completion: October 20, 2019
• Last Updated: August 23, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)