Autobiographical Memory Organization in Schizophrenia

NCT02570594 | Completed

• 1 other identifier: 5506
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to investigate the temporal organization of autobiographical memory in patients with schizophrenia. Patients and control participants will be invited separately to participate in a 1hour walk in the city of Strasbourg and at the same time, to carry an automatic camera around their neck, which is called SenseCam®. Pictures obtained with SenseCam® will be later presented to the participants during the session of test. They will be asked to determine the chronological order of 12 pictures corresponding to 12 particular events of the tour. Then they will be asked to watch the complete sequence of photos from the tour and to determine the beginning and ending of the events that have occurred during the tour. According to the investigators hypotheses, patients should have difficulty to find out the correct chronological order of the photos and to determine the appropriate beginnings and endings of the events

Conditions

Schizophrenia

Keywords

Cognition; Autobiographical; memoryCognitive; remediation

Outcome Measures

Primary Outcomes (1)

• Specificity of memories recovered by using the SenseCam camera during the trial

  SenseCam®(corresponding to the name of the automatic camera that participants will be asked to carry around their neck during the city-tour)

  1 month

Study Arms (1)

healthy volunteers

OTHER

Other: questionary

Interventions

questionary OTHER

healthy volunteers

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• for both patients and controls
• male or female willing to participate and who have signed up the legal document
• under the protection of health insurance for patients only
• schizophrenia or schizo-affective disorder according to the DSM-IV-TR criteria
• clinically stable for at least 2 months for controls only
• no psychiatric history

You may not qualify if:

• for both patients and controls
• current severe or unstable somatic illness
• neurological history (epilepsia, brain injury, brain surgery…)
• current substance use disorder (DSM-IV-TR)
• current major depressive disorder (DSM-IV-TR)
• mental retardation (IQ \< 70)
• pregnancy, breast feeding
• current legal control for patients only
• treatment comprising benzodiazepines
• benzodiazepines intake during the last 3 weeks for controls only
• psychotropic intake during the last 3 weeks

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de psychiatrie 1 , Les Hôpitaux Universitaires de Strasbourg

Strasbourg, Alsace, 67091, France

Location

Related Publications (1)

• Alle MC, Giersch A, Potheegadoo J, Meyer N, Danion JM, Berna F. From a Lived Event to Its Autobiographical Memory: An Ecological Study Using Wearable Camera in Schizophrenia. Front Psychiatry. 2019 Oct 4;10:699. doi: 10.3389/fpsyt.2019.00699. eCollection 2019.

  PMID: 31636574 RESULT

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 12, 2013
• First Posted: October 7, 2015
• Study Start: January 1, 2014
• Primary Completion: June 1, 2017
• Study Completion: June 1, 2017
• Last Updated: December 19, 2025

Record last verified: 2025-12

Locations

FR (1)