Key Insights

Highlights

Success Rate

91% trial completion (above average)

Published Results

682 trials with published results (23%)

Research Maturity

2045 completed trials (69% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

7.2%

214 terminated out of 2952 trials

Success Rate

90.5%

+3.9% vs benchmark

Late-Stage Pipeline

27%

792 trials in Phase 3/4

Results Transparency

33%

682 of 2045 completed with results

Key Signals

682 with results91% success214 terminated

Data Visualizations

Phase Distribution

2,528Total
Not Applicable (1039)
Early P 1 (22)
P 1 (333)
P 2 (342)
P 3 (378)
P 4 (414)

Trial Status

Completed2,045
Unknown310
Terminated214
Recruiting196
Not Yet Recruiting69
Withdrawn63

Trial Success Rate

90.5%

Benchmark: 86.6%

Based on 2045 completed trials

Clinical Trials (2952)

Showing 20 of 20 trials
NCT05206292Not ApplicableCompleted

Estimating Prevalence of Inherited Disorders of Sulfur Amino Acids Metabolism in Patients With Psychotic Disorders.

NCT07788755Not ApplicableNot Yet RecruitingPrimary

NEURO-COGS: Neurometabolic Mechanisms of Cognitive Training in Schizophrenia

NCT00001486Completed

Genetic Study of Schizophrenia

NCT00001246Active Not Recruiting

Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers

NCT07781007Not ApplicableNot Yet RecruitingPrimary

Effectiveness of a Board Game Intervention on Cognitive and Functional Outcomes in Older Adults With Schizophrenia

NCT07856368Not ApplicableRecruitingPrimary

Neuronavigated rTMS for Treatment-Resistant Auditory Hallucinations

NCT05491538Not ApplicableRecruitingPrimary

Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness

NCT07571148CompletedPrimary

Real-world Patient Characteristics, Treatment Patterns, and Healthcare Utilization Among KarXT Users

NCT05648591Phase 4RecruitingPrimary

Safety and Tolerability of Open-Labeled Iloperidone in Adolescents

NCT04798131Not ApplicableRecruitingPrimary

fMRI-based Neurofeedback to Relieve Drug-resistant Auditory Hallucinations

NCT07680114Not ApplicableRecruitingPrimary

Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls

NCT06118268Not ApplicableRecruitingPrimary

iTBS to Enhance Social Cognition in People With Psychosis

NCT00942981Completed

Functional Relevance of Dopamine Receptors in Healthy Controls and Patients With Schizophrenia: Characterization Through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography

NCT07101094RecruitingPrimary

Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

NCT05703412Not ApplicableEnrolling By Invitation

Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness

NCT03896945Phase 2TerminatedPrimary

Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Negative Symptoms of Schizophrenia

NCT07686263Phase 3RecruitingPrimary

Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia

NCT07615426Phase 1RecruitingPrimary

A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia

NCT07227818Phase 3RecruitingPrimary

Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia

NCT07105098Phase 3RecruitingPrimary

NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

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Research Network

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