The Effects of Spinal Manipulation on Central Nervous System Activity Measured by Reflexive Calf Muscle Recruitment

NCT02848456 | Completed

• 1 other identifier: 14-0507-F6A
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigated the effects of spinal manipulation on central nervous system activity. The presence of postactivation potentiation, an increase in muscular force production following prior muscular contractions, was measured with electromyography and the muscular force production during electrically-induced calf muscle reflexes. It was hypothesized that significantly greater potentiation would be stimulated by a calf muscle contraction with spinal manipulation delivered immediately beforehand than the potentiation arising from the contraction only.

Conditions

Subluxation of Joint of Lumbar Spine

Keywords

Manipulation, Spinal; H-Reflex; Muscle Contraction; Muscle Strength Dynamometer

Outcome Measures

Primary Outcomes (2)

• Changes in H-reflex amplitudes of the gastrocnemius and soleus muscles compared to baseline

  Peak-to-peak EMG amplitudes (mV) at Hmax of the gastrocnemius and soleus were recorded before and immediately following the three separate treatments

  Data were collected at 17 time points during a 20-minute tibial nerve electrical stimulation protocol post-treatment: 20 seconds, 40 seconds, 1:00, 2:00, 3:00, 4:00, 5:00, 6:00, 7:00, 8:00, 9:00, 10:00, 12:00, 14:00, 16:00, 18:00 and 20:00 minutes

• Changes in isometric twitch torques of the gastrocnemius and soleus muscles compared to baseline

  Twitch torques (Nm) of the gastrocnemius and soleus at Mmax were recorded before and immediately following the three separate treatments

  Data were collected at 17 time points during a 20-minute tibial nerve electrical stimulation protocol post-treatment: 10 seconds, 30 seconds, 50 seconds, 1:30, 2:30, 3:30, 4:30, 5:30, 6:30, 7:30, 8:30, 9:30, 11:00, 13:00, 15:00, 17:00 and 19:00 minutes

Study Arms (3)

Spinal Manipulation SM

ACTIVE COMPARATOR

In a repeated measures, crossover design, all subjects received one of three randomized treatments during three separate sessions: SM; a 10 second plantar flexion maximal voluntary isometric contraction (MVIC) or the manipulation immediately preceding the contraction (SM+MVIC).

Procedure: Spinal Manipulation

Max Voluntary Isometric Contraction MVIC

ACTIVE COMPARATOR

In a repeated measures, crossover design, all subjects received one of three randomized treatments during three separate sessions: SM; a 10 second plantar flexion maximal voluntary isometric contraction (MVIC) or the manipulation immediately preceding the contraction (SM+MVIC).

Procedure: Max Voluntary Isometric Contraction

SM+MVIC

ACTIVE COMPARATOR

In a repeated measures, crossover design, all subjects received one of three randomized treatments during three separate sessions: SM; a 10 second plantar flexion maximal voluntary isometric contraction (MVIC) or the manipulation immediately preceding the contraction (SM+MVIC).

Procedure: SM+MVIC

Interventions

Spinal Manipulation PROCEDURE

Manual, side-posture, high-velocity low-amplitude spinal manipulation targeting the lower lumbar spine and sacroiliac joints

Spinal Manipulation SM

Max Voluntary Isometric Contraction PROCEDURE

A 10 second plantar flexion maximal voluntary isometric contraction

Max Voluntary Isometric Contraction MVIC

SM+MVIC PROCEDURE

The spinal manipulation immediately preceding the maximal voluntary isometric contraction

SM+MVIC

Eligibility Criteria

• Age: 20 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• At least one year of resistance training experience and current completion of at least three training sessions per week
• Males needed to be able to back squat a minimum load of 1.5 x body weight
• Females needed to be able to back squat 1 x body weight

You may not qualify if:

• Any pain in the lower back, abdomen or legs and/or surgeries performed in these regions

Sponsors & Collaborators

• Grant Sanders: lead
• University of Kentucky: collaborator

Study Sites (1)

College of Education, Department of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY

Lexington, Kentucky, 40506, United States

Location

Related Publications (48)

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MeSH Terms

Interventions

Manipulation, Spinal

Intervention Hierarchy (Ancestors)

Musculoskeletal Manipulations; Physical Therapy Modalities; Therapeutics; Rehabilitation

Study Officials

• Grant D Sanders, D.C., Ph.D.

  College of Education, Department of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY

  PRINCIPAL INVESTIGATOR

• James W Yates, Ph.D.

  College of Education, Department of Kinesiology and Health Promotion, University of Kentucky, Lexington, KY

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 13, 2016
• First Posted: July 28, 2016
• Study Start: August 1, 2014
• Primary Completion: October 1, 2014
• Study Completion: October 1, 2014
• Last Updated: April 19, 2017

Record last verified: 2017-04

Data Sharing

• IPD Sharing: Will share

Locations

US (1)